Sökning: "antimicrobial drug resistance"

Visar resultat 6 - 10 av 47 avhandlingar innehållade orden antimicrobial drug resistance.

  1. 6. Extended-Spectrum ß-Lactamase-Producing Enterobacteriaceae : Antibiotic consumption, Detection and Resistance Epidemiology

    Författare :Åse Östholm Balkhed; Lennart Nilsson; Håkan Hanberger; Hans-Jurg Monstein; Anita Hällgren; Mats Kalin; Linköpings universitet; []
    Nyckelord :Extended-Spectrum ß-Lactamase-Producing Enterobacteriaceae; Antibiotic consumption; Detection Methods; Multiplex PCR; Resistance Epidemiology; Multi-resistance; E. coli; ESBL; fecal carriage; faecal carriage; travel;

    Sammanfattning : ESBL-producing Enterobacteriaceae are emerging worldwide and they are frequently multi-drug resistant, thus limiting treatment options for infections caused by these pathogens.The overall aim of the thesis was to investigate ESBL-producing Enterobacteriaceae in a Swedish county. LÄS MER

  3. 7. Polymeric Nanoparticles as Carriers for Antimicrobial Peptides : Factors Affecting Peptide and Membrane Interactions

    Författare :Randi Nordström; Martin Malmsten; Per Hansson; Helena Bysell; Erica Wanless; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; antimicrobial peptide; microgel; degradable; nanogel; drug delivery; PEGylation; secondary structure; model membrane; lipid bilayer; neutron reflectometry; ellipsometry; Pharmaceutical Physical Chemistry; Farmaceutisk fysikalisk kemi;

    Sammanfattning : As resistance towards conventional antibiotics is becoming more pronounced, cationic antimicrobial peptides (AMPs) have received considerable attention as possible therapeutic alternatives. Thousands of potent AMPs occur in humans, animals, plants and fungi as a natural part of the immune system. LÄS MER

  4. 8. Quantifying effects of antimicrobial drug combinations by modelling and simulation

    Författare :Chenyan Zhao; Lena Friberg; Elisabet I. Nielsen; Shampa Das; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacokinetics and pharmacodynamics; modelling and simulation; antibiotic combination; model-based translation; antibiotic resistance; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : Antibiotic resistance is becoming an accelerating issue, both in the treatment of nosocomial infections and for public health in general. There is a pressing need for innovative methods to understand how available antibiotics could be combined to overcome and limit the emergence of resistance. LÄS MER

  5. 9. Surveillance of Antibiotic Consumption and Antibiotic Resistance in Swedish Intensive Care Units

    Författare :Marcus Erlandsson; Håkan Hanberger; Nils Smith-Erichsen; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bacterial Antibiotic resistance; Antibiotic Consumption; ICU; Surveillance programme; Multi drug resistance; Pseudomonas aeruginosa; ICU demography; Infectious diseases; Infektionssjukdomar;

    Sammanfattning : Introduction: Nosocomial infections remain a major cause of mortality and morbidity. The problem is most apparent in intensive care units (ICUs). Most ICU patients are compromised and vulnerable as a result of disease or severe trauma. One in ten people admitted to hospital is given an antibiotic for infection. LÄS MER

  7. 10. Lipid-based liquid crystals as drug delivery vehicles for antimicrobial peptides

    Författare :Lukas Boge; Chalmers tekniska högskola; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; hexosome; antimicrobial peptide; cubosome; proteolysis; AMP; liquid crystalline nanoparticles; glycerol monooleate; Liquid crystals;

    Sammanfattning : The development of antimicrobial resistance is a great challenge within the health sector around the world. The demand for new efficient treatments is alarming in order to treat various bacterial infections in the near future. Antimicrobial peptides (AMPs) are a group of novel antibiotics that have gain more and more attraction the past decade. LÄS MER