Sökning: "antimicrobial drug resistance"

Visar resultat 21 - 25 av 47 avhandlingar innehållade orden antimicrobial drug resistance.

  1. 21. Bacterial thioredoxin systems as potential drug targets in novel antimicrobial therapies

    Författare :Tomas N Gustafsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Antimicrobial resistance is a big problem in modern medicine. One of the key components in the combat is the characterization of novel drug targets and the development of new classes of compounds targeting them. LÄS MER

  3. 22. Antibiotic resistance and pathogenesis of Streptococci with focus on Group A Streptococci

    Författare :Feiruz Alamiri; Malmö Experimentell infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Antibiotika resistens; Bröstmjölk; Luftvägsinfektioner; Biofilm bildning; Internalisering; Persistens; HAMLET; Streptokocker; kolonisering; Streptococcus pneumoniae; biofilm formation; Internalisation; Persistence; Antibiotic resistance; Streptococcus pyogenes; Streptococcus agalactiae; HAMLET; Breast milk; Proteome; Virulence factors; Colonization;

    Sammanfattning : Multi-drug resistant (MDR) infections remain the leading cause of death worldwide. MDR infections caused by Streptococcus pneumoniae (Spn), Streptococcus pyogenes (GAS) and Streptococcus agalactiae (GBS) are considered global threats to human health due to increased spread of antibiotic resistance and limited treatment options. LÄS MER

  4. 23. Ecological disturbances and emergence of resistance in the oral and gastrointestinal microflora after drug exposure

    Författare :Christina Stark; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :ecology antimicrobial resistance oral gastrointestinal microflora B-lactamase enzyme induction.;

    Sammanfattning : The exposure of antimicrobial agents and antacids may disturb the ecological balance of the normal microflora. This influence often leads to decreased colonization resistance due to repression of sensitive bacteria and selection of resistant bacteria which have acquired resistance during therapy. LÄS MER

  5. 24. Microbial Responses to Antibiotics – Stability of Resistance and Extended Potential of Targeting the Folate Synthesis

    Författare :Maria Jönsson; Göte Swedberg; Steven Meshnick; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; sulfonamide resistance; macrolide; commensal flora; substrate channeling; folate synthesis; Molekylärbiologi; Molecular biology; Molekylärbiologi;

    Sammanfattning : Resistance to antimicrobials is an increasing problem in the world of today, and develops faster than man can counter. It is therefore of importance to study metabolic pathways in order to develop new antibiotics, but also to understand how resistance spreads and stabilizes in microbial populations. LÄS MER

  7. 25. Bacteria-responsive materials for drug delivery

    Författare :Marina Craig; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; triggered release; multilayer; controlled release; Layer-by-layer; nanofilm; infection; enzymatic degradation;

    Sammanfattning : The number of diabetics, obese individuals and other patients carrying other lifestyle diseasesis increasing worldwide. At the same time the population is ageing. These patients all sufferfrom poor blood circulation, which often gives rise to non-healing, or chronic, wounds. Thus,the number of chronic wounds is also increasing at a fast pace. LÄS MER