Sökning: "aktivering"

Visar resultat 31 - 35 av 269 avhandlingar innehållade ordet aktivering.

1. 31. Trypsinogen and Its Activation in Acute Pancreatitis

   Författare :Ulf Petersson; Kirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TAP; ERCP; carboxypeptidase B activation peptide; trypsinogen activation peptide; trypsinogen activation; Acute pancreatitis; trypsinogen; CAPAP; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi;

   Sammanfattning : Pancreatic enzymes, neutrophils, free radicals and cytokines are involved in the pathophysiology of AP. Clarification of their interaction and time-course will improve our understanding of AP and provide a better basis for treatment. LÄS MER

3. 32. Regulation of PKCalpha and the role of PKC in neuroblastoma cell migration

   Författare :Helena Stensman; Institutionen för translationell medicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cytology; oncology; cancerology; Cytologi; Medicin människa och djur ; Medicine human and vertebrates ; neuroblastoma; cell migration; intramolecular interactions; autophosphorylation; Protein kinase C; onkologi; cancer;

   Sammanfattning : Members of the protein kinase C (PKC) family of serine/threonine kinases play critical roles in cellular regulation. Depending on differences in regulation, PKCs can be divided into classical (alpha, betaI, betaII and gamma), novel (delta, epsilon, eta and theta) and atypical (zeta and iota/lambda) isoforms. LÄS MER

4. 33. Nitrates and Left Ventricular Dysfunction

   Författare :Erik Tingberg; Kardiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lipid peroxidation; malondialdehyde; peptide; brain natriuretic peptide; left ventricular dysfunction; nitrates; acute myocardial infarction; heart failure; atrial natriuretic; diuretics; echocardiography; haemodynamic measurements; neurohumoral activation; diastolic dysfunction; Cardiovascular system; Medicin människa och djur ; Medicine human and vertebrates ; Kardiovaskulära systemet; oxidative stress; isoprostanes;

   Sammanfattning : Use of beta-blockers and inhibitors of the renin angiotensin system (RAS) is established practice in the treatment of chronic heart failure (CHF). Clinical studies also suggest beneficial long-term effects of nitrates in CHF. LÄS MER

5. 34. Inflammatory response and intervention in experimental acute pancreatitis

   Författare :Changbin Shi; Lund Kirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kirurgi; ortopedi; traumatologi; traumatology; Surgery; orthopaedics; signalling pathways; protein kinase C; nuclear factor-kB; leukocytes; inflammatory mediators; immunosuppression; acute pancreatitis; extracellular signal-regulated kinase;

   Sammanfattning : Acute pancreatitis (AP) is a common disease where underlying mechanisms for the local initiating events in the pancreas, the systemic dissemination of the inflammatory response and remote organ dysfunction still are unclear. The overall aim of the thesis was to study mechanisms of the inflammatory response in AP with special emphasis on local, systemic, and distant organ injury directed at different signalling pathways, and potential therapeutic strategies to prevent the development of inflammation and cell injury following AP. LÄS MER

7. 35. Role of adhesion molecules and chemokines in TNF-alpha-induced leukocyte recruitment

   Författare :Xiao Wei Zhang; Kirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; intravital microscopy; microcirculation; inflammation; adhesion; leukocyte; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi;

   Sammanfattning : Migration of leukocytes from the circulating blood into the extravascular tissue is a key component in inflammatory reactions. Leukocyte extravasation (rolling-activation-adhesion-transmigration) is strictly coordinated by adhesion molecules and chemokines expressed on cell surfaces and in tissues. LÄS MER