Sökning: "trypsinogen activation"

Visar resultat 1 - 5 av 8 avhandlingar innehållade orden trypsinogen activation.

  1. 1. Trypsinogen and Its Activation in Acute Pancreatitis

    Författare :Ulf Petersson; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TAP; ERCP; carboxypeptidase B activation peptide; trypsinogen activation peptide; trypsinogen activation; Acute pancreatitis; trypsinogen; CAPAP; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi;

    Sammanfattning : Pancreatic enzymes, neutrophils, free radicals and cytokines are involved in the pathophysiology of AP. Clarification of their interaction and time-course will improve our understanding of AP and provide a better basis for treatment. LÄS MER

  3. 2. Trypsinogen and neutrophil activation in acute Pancreatitis

    Författare :Hannes Hartman Magnusson; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute pancreatitis; trypsinogen activation; adhesion; neutrophil extracellular traps;

    Sammanfattning : Background and aims: Acute pancreatitis (AP) is a common condition characterized by premature protease activation, abdominal pain and leakage of pancreatic enzymes to the circulation. Approximately 10% develop systemic inflammation and persistent organ failure. LÄS MER

  4. 3. Acute Pancreatitis. Studies on smoking and protease activation

    Författare :Björn Lindkvist; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; trypsinogen; Acute pancreatitis; trypsinogen activation peptide cathepsin B; incidence; smoking; nicotine; traumatologi; ortopedi; Kirurgi; traumatology; Surgery; orthopaedics; Gastroenterologi; Public health; epidemiology; Folkhälsa; epidemiologi; Gastro-enterology;

    Sammanfattning : Background and aims: Activation of pancreatic proteases is considered to be a crucial event in the early phase of acute pancreatitis but the cause of this activation is not known. Most cases of acute pancreatitis can be attributed to either gallstone disease or alcohol abuse. However, little is known about other risk factors. LÄS MER

  5. 4. Role of platelets and neutrophils in regulating trypsinogen activation and tissue damage in acute pancreatitis

    Författare :Aree Abdulla; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Protease activation; adhesion molecule; chemokine; intravital flourecence microscopy; matrix metalloproteinase.;

    Sammanfattning : Acute pancreatitis is an inflammatory disease characterized by a diverse spectrum of clinical presentations ranging from a mild and self-limiting to a severe and systemic disorder. The relationship between inflammation and proteolytic activation in pancreatitis is an elusive issue. LÄS MER

  7. 5. Signaling and Adhesive Mechanisms in Acute Pancreatitis

    Författare :Darbaz Awla; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; trypsinogen activation; Acute pancreatitis; leukocyte recruitment and adhesion;

    Sammanfattning : Acute pancreatitis (AP) is an inflammatory disease with variable severity ranging from mild interstitial edematous to severe necrotizing disease. The overall mortality rate of AP is 8-9%. Specific treatment of AP is lacking which is partly related to an incomplete understanding of the basic pathophysiology behind the disease. LÄS MER