Sökning: "isoprostanes"

Visar resultat 1 - 5 av 16 avhandlingar innehållade ordet isoprostanes.

  1. 1. Dietary Fatty Acids and Inflammation : Observational and Interventional Studies

    Författare :Helena Bjermo; Ulf Risérus; Tommy Cederholm; Parveen Yaqoob; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES; Dietary fat; Fatty acids; Serum fatty acid composition; Linoleic acid; Stearoyl coenzymeA desaturase; SCD-1; Inflammation; C-reactive protein; Oxidative stress; Lipid peroxidation; Isoprostanes; Prostaglandins; Obesity; Epidemiology; Dietary intervention; Metabolic syndrome; Nutrition; Näringslära; Epidemiology; Epidemiologi; Public health science; Folkhälsovetenskap; Immunology; Immunologi; Diabetology; Diabetologi; Cardiology; Kardiologi; Medical Science; Medicinsk vetenskap;

    Sammanfattning : Dietary fat quality influences the risk of type 2 diabetes and cardiovascular disease. A low-grade inflammation is suggested to contribute to the disease development, often accompanied by obesity. Whereas n-3 polyunsaturated fatty acids (PUFA) have been considered anti-inflammatory, n-6 PUFA have been proposed to act pro-inflammatory. LÄS MER

  2. 2. Oxidative stress, antioxidative defence and outcome of gestation in experimental diabetic pregnancy

    Författare :Jonas Cederberg; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Diabetes; pregnancy; rat; ROS; free oxygen radicals; TBARS; isoprostanes; protein carbonyls; embryo; vitamin C; vitamin E; Cellbiologi; Cell biology; Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Sammanfattning : Maternal type 1 diabetes is associated with an increased risk for foetal malformations. The mechanism by which diabetes is teratogenic is not fully known. Previous studies have demonstrated that radical oxygen species can contribute to the teratogenicity of glucose and diabetes. LÄS MER

  3. 3. Diet and Metabolic Risk Factors in Immigrant Women from the Middle East and Swedish-Born Women : A Cross-Sectional Study of Women from Iran, Turkey and Sweden

    Författare :Achraf Daryani; Bengt Vessby; Brita karlström; Per Wändell; Uppsala universitet; []
    Nyckelord :Caring sciences; cardiovascular factors; metabolic risk factors; immigrants; Iranian; Turkish; Swedish; Middle East; dietary intake; underreporting; dietary fat; fat sources; antioxidant intake; oxidative stress; inflammation; C-reactive protein; isoprostanes; Vårdvetenskap;

    Sammanfattning : The increasing number of immigrants in Sweden during the past decades has brought the health of different ethnic groups into focus. Many groups of immigrants in Sweden have a higher risk of cardiovascular disease (CVD) and coronary heart disease (CHD) than a Swedish reference group. LÄS MER

  4. 4. Pathophysiological, Inflammatory and Haemostatic Responses to Various Endotoxaemic Patterns : An Experimental Study in the Pig

    Författare :Miklós Lipcsey; Mats Eriksson; Jan Sjölin; Anders Larsson; Anders Bengtsson; Uppsala universitet; []
    Nyckelord :Anaesthesiology and intensive care; sepsis; animal model; cytokines; isoprostanes; endotoxic shock; pig; Anestesiologi och intensivvård;

    Sammanfattning : Septic shock is frequently seen in intensive care units and is associated with significant mortality. Endotoxin – a major mediator of the pathophysiologic responses – is released during lysis of Gram-negative bacteria. These responses can be mimicked in the endotoxaemic pig. LÄS MER

  5. 5. Effect of Dietary Antioxidants on Oxidative Stress, Inflammation and Metabolic Factors : Studies in Subjects with Overweight and with Type 2 Diabetes

    Författare :Elisabet Rytter; Samar Basu; Bengt Vessby; Anders Sjödin; Helmut Sies; Uppsala universitet; []
    Nyckelord :Antioxidants; supplementation; fruit and vegetables; oxidative stress; isoprostanes; lipid peroxidation; oxidative damage to DNA; glycaemic control; inflammation; overweight; type 2 diabetes; MEDICINE; MEDICIN; Nutrition; Nutrition;

    Sammanfattning : Observational studies have indicated that fruit and vegetables, and dietary antioxidants may play an important role in reducing the risk of chronic diseases, potentially by affecting pathogenic mechanisms such as oxidative stress and inflammation. Clinical trials investigating the effects of supplementation with single or a few antioxidants in high doses have, however, shown inconsistent results and thus have not been able to support the observational findings. LÄS MER