Sökning: "Toll-Like Receptor 2"

Visar resultat 6 - 10 av 49 avhandlingar innehållade orden Toll-Like Receptor 2.

  1. 6. Stroke recovery activity-dependent mechanisms

    Författare :Miriana Quattromani; Neurokirurgi; []
    Nyckelord :Stroke recovery; Photothrombosis; Enriched environment; Bioluminescence imaging; Toll-like receptor 2; Microglia; Neurons; Extracellular matrix; Perineuronal nets; Aggrecan; Proteases; Parvalbumin; Resting-state functional connectivity;

    Sammanfattning : Stroke is the leading cause of disability in developed countries and among the major causes of death worldwide. During a stroke, neurons deprived of their normal metabolic substrates cease to function in seconds and show signs of structural damage after only a few minutes which result in the impairment of sensory and motor function. LÄS MER

  3. 7. Preterm and term cervical ripening : studies on CRH, HMGB1, toll-like receptors, cytokines and matrix metalloproteinases

    Författare :Aurelija Dubicke; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cervical fibroblasts; cervical ripening; cervix; chemokines; cytokines; CRH; HMGB1; interleukin; labor; preterm; preterm labor; matrix metalloproteinases; pregnancy; PPROM; Tolllike receptors;

    Sammanfattning : Objective: Preterm birth (PTB) is the leading cause of neonatal mortality and morbidity. Despite the existing treatment, the frequency of PTB has not changed in the past thirty years. Incomplete understanding of the biological and pathophysiological mechanisms underlying preterm delivery is the major obstacle to preventing PTB. LÄS MER

  4. 8. Immune regulation of herpes simplex virus type 2 infection: Special emphasis on the transcription factor T-bet

    Författare :Alexandra Svensson; Göteborgs universitet; []
    Nyckelord :HSV-2; T-bet; Substance P; Neurokinin 1; IFN-alfa beta signaling; Polymorphisms;

    Sammanfattning : Herpes simplex virus type 2 (HSV-2) is a sexually transmitted pathogen that infects the genital tract mucosa as well as local sensory neurons. It is the most common cause of genital ulcer disease in humans. The infection gives rise to a wide range of symptoms, ranging from severe and painful recurrent episodes of genital herpes to silent infection. LÄS MER

  5. 9. Microbial regulation of PPARgamma : nuclear receptor networks important for colonic homeostasis

    Författare :Linda Aronsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : One of the central issues surrounding the physiology of good health is to uncover and understand the molecular networks responsible for its maintenance. The alimentary tract in particular, demands a properly sustained homeostatic control since it is constantly challenged by potentially harmful agents along with innocuous nutrients, with the burden of basic metabolic functions in its ward. LÄS MER

  7. 10. Mechanisms of liver allograft rejections

    Författare :Xupeng Ge; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Liver transplantation; acute rejection; antibody; biliary epithelial cell; sinusoidal endothelial cell; cholangitis; toll-like receptor;

    Sammanfattning : Liver transplantation (M) has become a standard treatment for many end-stage liver diseases. However, acute rejections still occur in about half of the liver transplant recipients even treated with a combination of different modem immunosuppressants. LÄS MER