Sökning: "Synapses"
Visar resultat 1 - 5 av 133 avhandlingar innehållade ordet Synapses.
1. On the Nature of β-Amyloid at Synapses
Sammanfattning : Alzheimer’s disease is an aging related disorder of the mind, accountable for 60-80 percent of all cases of dementia. With its insidious progression and the decline of cognitive abilities, this disease is a major challenge for our society as a whole. LÄS MER
2. Characterization of Physiological and Pathological Alpha-Synuclein : Implications for Parkinson’s Disease and Related Disorders
Sammanfattning : Aggregated alpha-synuclein is the main component of Lewy bodies and Lewy neurites, intraneuronal inclusions found in the brains of Parkinson’s disease (PD) and dementia with Lewy bodies (DLB) patients (synucleinopathies). Alpha-synuclein is a presynaptic protein, which is most commonly an unfolded monomer in its physiological state. LÄS MER
3. Neuroinflammation and amyloid-β in early Alzheimer’s disease. Insight into the earliest events using mouse models
Sammanfattning : Alzheimer’s disease (AD) is the leading cause of dementia and most common neurodegenerative disease worldwide, but there currently exists no effective treatment that can stop nor slow the progression of the disease. The current dogma in the field postulates that the appearance of extracellular amyloid-beta (Aβ) plaques, a histopathological hallmark of the disease, is the trigger for downstream, detrimental events, including neuronal loss, extensive neuroinflammation and cognitive decline. LÄS MER
4. The synaptic and neurobiological role of apolipoprotein E4 in models of Alzheimer's disease
Sammanfattning : .... LÄS MER
5. Flexible Electrical and Photoelectrical Artificial Synapses for Neuromorphic Systems
Sammanfattning : Over the past decade, the field of personal electronic systems has trended toward mobile and wearable devices. However, the capabilities of existing electronic systems are overwhelmed by the computing demands at the wearable sensing stage. Two main bottlenecks are encountered. LÄS MER