Sökning: "Sun Nyunt Wai"
Visar resultat 6 - 10 av 10 avhandlingar innehållade orden Sun Nyunt Wai.
6. Host-pathogen interactions during Campylobacter and Yersinia infections
Sammanfattning : The innate immune system is known for protecting the host against invading pathogens, for instance enteropathogens infecting the gastrointestinal tract. The production of e.g. antimicrobial peptides, cytokines, and chemokines by innate immune cells and intestinal epithelial cells contribute to bacterial clearance. LÄS MER
7. Roles of secreted bacterial factors in modulation of host cell signalling
Sammanfattning : Pathogenic bacteria employ several secretion systems to release or inject virulence factors that may alter host cell processes, generate a replicative niche, and aid bacterial survival in adverse environments. This thesis presents my investigations on how bacterial factors can modulate host cell signalling mechanisms. LÄS MER
8. Effects of Vibrio cholerae protease and pigment production on environmental survival and host interaction
Sammanfattning : Only two out of more than 200 V. cholerae serogroups, classified on the basis of LPS structure, are associated with epidemic or pandemic cholera. These toxigenic serogroups carry phage-derived pathogenicity islands coding for the main virulence factors for establishment of cholera disease – cholera toxin (CTX) and toxin-coregulated pilus (TCP). LÄS MER
9. Roles of membrane vesicles in bacterial pathogenesis
Sammanfattning : The production of membranous vesicles is observed to occur among organisms from all domains of the tree of life spanning prokaryotes (bacteria, archaea) and eukaryotes (plants, animals and fungi). Bacterial release of membrane-derived vesicles (MVs) has been studied most extensively in cases of Gram-negative species and implicating their outer membrane in formation of extracellular MVs. LÄS MER
10. Regulatory mechanisms involved in pathoadaptation of extraintestinal pathogenic Escherichia coli
Sammanfattning : Establishment of commensal bacteria within a new niche of their host usually promotes the transition from commensalism to pathogenicity. Extraintestinal Pathogenic Escherichia coli (ExPEC) represent different pathovars with biphasic lifestyle – they can reside in the gut as commensals or they can escape and cause diseases elsewhere in the human body. LÄS MER