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Visar resultat 21 - 25 av 427 avhandlingar som matchar ovanstående sökkriterier.

  1. 21. Mechanisms of Integrin Signal Transduction

    Författare :Anne Stefansson; Staffan Johansson; Annika Armulik; Björn Öbrink; Uppsala universitet; []
    Nyckelord :Cell biology; Integrin; Integrin signalling; PI3K; Akt PKB; Integrin transmembrane domain; cell spreading; Cellbiologi;

    Sammanfattning : Integrins are a protein family of cell surface receptors, expressed in all cell types in the human body, except the red blood cells. Besides their importance in mediating physical connections with the surrounding environment, the integrin family members are also vital signalling mediators. LÄS MER

  2. 22. Incorporation of Departure Time Choice in a Mesoscopic Transportation Model for Stockholm

    Författare :Ida Kristoffersson; Leonid Engelson; Jan Lundgren; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Transport Modelling; Departure Time Choice; Dynamic Traffic Simulation; Time-Varying Congestion Charges; Peak Spreading; Reverse Engineering;

    Sammanfattning : Travel demand management policies such as congestion charges encourage car-users to change among other things route, mode and departure time. Departure time may be especially affected by time-varying charges, since car-users can avoid high peak hour charges by travelling earlier or later, so called peak spreading effects. LÄS MER

  3. 23. Mechanisms of Brain Damage Following Focal Cerebral Ischemia: Changes in Ion Homeostasis and the Importance of Free Radical Formation

    Författare :Gunilla Gidö; Sektion IV; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PBN; free radicals; potassium; extracellular calcium; neuronal damage; energy-depletion; hypoglycemia; Cerebral focal ischemia; spreading depression; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

    Sammanfattning : In this thesis mechanisms of neuronal damage were investigated in an experimental stroke model i.e focal ischemia. The influence of SD-induced calcium transients on neuronal damage were studied in animals with reduced energy supply. LÄS MER

  4. 24. Numerical simulation of non-Newtonian fluids flow over surfaces

    Författare :Kazem Bazesefidpar; Outi Tammisola; Luca Brandt; Shahriar Afkhami; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; dynamic wetting; viscoelasticity; non-Newtonian fluids; contact- angle hysteresis; droplet spreading; self-propelled jumping; dynamisk vätning; viskoelasticitet; icke-Newtonska vätskor; kontaktlinjehysteres; dropparnas spridning på ytor; spontan hoppning av droppar från ytor; Teknisk mekanik; Engineering Mechanics;

    Sammanfattning : Wetting of surfaces by droplets of non-Newtonian fluids is important for various industrial and natural processes such as coating and cleaning of surfaces and inkjet printing, to name a few. Viscoelastic fluids are compounds of a very small amount of polymers and solvent. LÄS MER

  5. 25. Effects of invasin and YopH of Yersinia pseudotuberculosis on host cell signaling

    Författare :Anna Gustavsson; Maria Fällman; Arnoud Sonnenberg; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; β1-integrin; Yersinia pseudotuberculosis; Invasin; YopH; Cell-Matrix Adhesion; Filopodia; Cell Spreading; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : Integrins are a large family of membrane-spanning heterodimeric (αβ) receptors that bind to ligands on other cells or to extracellular matrix (ECM) proteins. These receptors mediate bidirectional signaling over the cell membrane to induce signaling cascades mediating functions as cell adhesion, spreading and migration. LÄS MER