Sökning: "Cerebral focal ischemia"

Visar resultat 1 - 5 av 31 avhandlingar innehållade orden Cerebral focal ischemia.

  1. 1. Astrocyte metabolism following focal cerebral ischemia

    Författare :Anna E Thoren; Göteborgs universitet; []
    Nyckelord :Astrocyte; metabolism; focal cerebral ischemia; reperfusion; infarct; [1-14C]acetate; [U-14C]glucose; glutamine; glutamate; ATP; ADP; lactate; MCT4; immunogold cytochemistry;

    Sammanfattning : Stroke is one of the leading causes of disability and death. Most often, stroke results from blockage of an artery in the brain leading to tissue infarction within the perfusion territory of the affected vessel. LÄS MER

  3. 2. Hyperglycemia and Focal Brain Ischemia : Clinical and Experimental Studies

    Författare :Nasim Farrokhnia; Andreas Terént; Fredrik Lennmyr; Elisabeth Björk; Henrik Hagberg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Internal medicine; cerebrovascular disorders; diabetes mellitus; hyperglycemia; infarction; middle cerebral artery; ischemia; mitogen-activated protein kinases; mortality; rats; reactive oxygen species; reperfusion; signal transduction; therapeutics; Invärtesmedicin; Internal medicine; Invärtesmedicin;

    Sammanfattning : Diabetes is a major risk factor for ischemic stroke and is associated with increased mortality. Additionally, hyperglycemia, a common complication in acute stroke, is associated with poor outcome. LÄS MER

  4. 3. Signal Transduction in Focal Cerebral Ischemia : Experimental Studies on VEGF, MAPK and Src family kinases

    Författare :Fredrik Lennmyr; Andreas Terént; Tommy Olsson; Uppsala universitet; []
    Nyckelord :Medical sciences; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicin; Medicine;

    Sammanfattning : Cerebral ischemia elicits a wide range of events, including complex activation of various intracellular signaling pathways. This study aims to investigate the expression of vascular endothelial growth factor (VEGF) and the activation pattern of mitogen-activated protein kinases (MAPK) in reponse to focal cerebral ischemia. LÄS MER

  5. 4. Hyperglycemia in Experimental Cerebral Ischemia

    Författare :Maria Molnar; Fredrik Lennmyr; Sten Lindahl; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; brain ischemia; cardiac arrest; cytokines; gene expression; glucose; hyperglycemia; microarray; oxidative stress; pigs; rats; reperfusion; resuscitation S100β; Anaesthesiology and Intensive Care; Anestesiologi och intensivvård; Neuroscience; Neurovetenskap;

    Sammanfattning : Cerebral ischemia is a life-threatening condition associated with a substantial morbidity and mortality. Hyperglycemia, a common coexisting phenomenon in both stroke and cardiac arrest (CA), may further aggravate ischemic brain injury. To date, the therapeutic possibilities are lim-ited and the search for new treatment modalities is warranted. LÄS MER

  7. 5. Cerebral ischemia studied with positron emission tomography and microdialysis

    Författare :Peter Frykholm; Peter Kirkpatrick; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Cerebral ischemia; penumbra; positron emission tomography; microdialysis; middle cerebral artery occlusion; Neurovetenskap; Neurology; Neurologi; Neurosurgery; neurokirurgi;

    Sammanfattning : Stroke is the third leading cause of morbidity and mortality in the industrialized world. Subarachnoid hemorrhage (SAH), the least common form of stroke, is one of the most demanding diseases treated in neurointensive care units. Cerebral ischemia may develop rapidly, and has a major influence on outcome. LÄS MER