Sökning: "Small non-coding RNAs"

Visar resultat 1 - 5 av 42 avhandlingar innehållade orden Small non-coding RNAs.

1. 1. Small non-coding RNAs in cancer

   Författare :Helena Persson; Bröstcancer-genetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; microRNA; non-coding RNA; breast cancer; CYP3A4; bladder cancer;

   Sammanfattning : The complex genetics of cancer, which allows tumours to grow and spread while bypassing the control circuitry of the cell, involves dysregulation of the genome, transcriptome and proteome. The importance of protein-coding genes such as growth factors and hormone receptors is well established. LÄS MER

3. 2. Adenoviral small non-coding RNAs : A Structural and Functional Charaterization

   Författare :Wael Kamel; Göran Akusjärvi; Ben Berkhout; Uppsala universitet; []
   Nyckelord :non-coding RNA miRNA mivaRNA canonical Dicer Ago2 TSS m7G Cap Adenovirus replication E2B;

   Sammanfattning : Since their discovery in 1953, adenoviruses have significantly contributed to the understanding of virus-host cell interactions, including mechanistic details of cellular processes such as cell cycle control and alternative RNA splicing. Among the first characterized adenoviral genes were the virus-associated RNAs (VA RNAI/II), which are produced in massive amount during a lytic infection. LÄS MER

4. 3. Small RNAs, Big Consequences : Post-transcriptional Regulation and Adaptive Immunity in Bacteria

   Författare :Mirthe Hoekzema; Gerhart E. H. Wagner; Magnus Lundgren; Kai Papenfort; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; small RNA; sRNA; non-coding RNA; Hfq; gene regulation; post-transcriptional regulation; biofilm; OmrA; OmrB; toxin-antitoxin; TisB; IstR-1; Persisters; CRISPR-Cas; CRISPR-Cas adaptation reporter; Escherichia coli; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

   Sammanfattning : It is nowadays widely accepted that non-coding RNAs play important roles in post-transcriptional regulation of genes in all kingdoms of life. In bacteria, the largest group of RNA regulators are the small RNAs (sRNAs). LÄS MER

5. 4. Macromolecular Matchmaking : Mechanisms and Biology of Bacterial Small RNAs

   Författare :Erik Holmqvist; E. Gerhart H. Wagner; Udo Bläsi; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Small RNA; sRNA; non-coding RNA; antisense; gene regulation; post-transcriptional regulation; translational control; outer membrane protein; OmpA; MicA; biofilm; flagella; curli; bistability; Lrp; MicF; CsgD; FlgM; OmrA; OmrB; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

   Sammanfattning : Cells sense the properties of the surrounding environment and convert this information into changes in gene expression. Bacteria are, in contrast to many multi-cellular eukaryotes, remarkable in their ability to cope with rapid environmental changes and to endure harsh and extreme milieus. LÄS MER

7. 5. Small non-coding RNA in early fly development : plasticity, interactions and improved bioinformatic tools

   Författare :Lovisa Örkenby; Anita Öst; Rashmi Ramesh; Daniel Nätt; Nicola Iovino; Linköpings universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Drosophila; Maternal-to-zygotic transition; sncRNA; miRNA; piRNA; Embryogenesis; Zygotic gene activation;

   Sammanfattning : At fertilization, the male and female pronuclei undergo a transformation from germline to pluripotency as they fuse, marking the beginning of Drosophila embryogenesis. As the parental contributions decrease, the zygote takes control of its genome in a process called the maternal-to-zygotic transition (MZT). LÄS MER