Sökning: "QTL Analysis"

Visar resultat 16 - 20 av 52 avhandlingar innehållade orden QTL Analysis.

  1. 16. Correlated selection responses in animal domestication : the behavioural effects of a growth QTL in chickens

    Författare :Anders Wirén; Per Jensen; Elena Jazin; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : Studying animal domestication offers an opportunity to understand the mechanisms of evolution. Domestication is associated with a change in selection pressures; selection for production traits is introduced, and animals are faced with larger and denser social groups. LÄS MER

  3. 17. Genetic analysis of autoimmune and metabolic traits in chickens

    Författare :Weronica Ek; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Studying how changes in DNA affect organisms and gene functions, can give us an increased understanding of the genetic regulation of diseases and metabolic traits. Chickens and other farm animals have long been used as a tool to study human diseases and other complex traits since they provide an excellent opportunity to study these traits in a controlled environment. LÄS MER

  4. 18. Selection during Early Life Stages and Local Adaptation in Arabidopsis thaliana

    Författare :Froukje M. Postma; Jon Ågren; Kathleen Donohue; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Dormancy cycling; Germination timing; Maternal effects; Natural variation; QTL mapping; Seed bank; Seed dormancy; Structural Equation Modeling; Biology with specialization in Ecological Botany; Biologi med inriktning mot ekologisk botanik;

    Sammanfattning : Organisms are often adapted to their local environment, but the role of early life stages in adaptive differentiation among populations remains poorly known. The aim of my thesis was to investigate the contribution of early life stages to the magnitude and genetic basis of local adaptation, and to identify the underlying adaptive traits. LÄS MER

  5. 19. Positional identification and functional analysis of genes regulating autoimmune arthritis

    Författare :Anthony Chun Yeung Yau; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The major histocompatibility complex (MHC) is the most gene-dense and polymorphic region in the human genome with strong associations to many autoimmune disorders, including rheumatoid arthritis (RA). However, even the genetic association between MHC and RA was known more than 40 years ago, we still have not fully explained the functional roles of the MHC genes and identified the underlying specific polymorphisms. LÄS MER

  7. 20. Genetic Factors and Nasal Tolerance in Rat Models for Rheumatoid Arthritis

    Författare :Shemin Lu; Immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nasal tolerance; linkage analysis; MHC; genetics; pristane induced arthritis; rheumatoid arthritis; collagen induced arthritis; Immunology; serology; transplantation; Immunologi; serologi;

    Sammanfattning : We used three animal models of rats for rheumatoid arthritis (RA) in this study. Firstly, We found that CXI induced arthritis (CXIIA) is associated with the RT1 f haplotype and follows a chronic disease course affecting peripheral joints with both progression and relapses. LÄS MER