Sökning: "pristane induced arthritis"
Visar resultat 1 - 5 av 13 avhandlingar innehållade orden pristane induced arthritis.
- Detta är en avhandling från Medical Inflammation Research, Department of Experimental Medicine, Faculty of Medicine, Lund University
Sammanfattning : We used three animal models of rats for rheumatoid arthritis (RA) in this study. Firstly, We found that CXI induced arthritis (CXIIA) is associated with the RT1 f haplotype and follows a chronic disease course affecting peripheral joints with both progression and relapses. LÄS MER
- Detta är en avhandling från Department of Experimental Medical Science, Lund Univeristy
Sammanfattning : Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation of the peripheral joints that eventually leads to cartilage destruction and bone erosion. The causes of RA remain largely unknown, but considerable evidence suggests a multifactorial aetiology involving both environmental and genetic factors. LÄS MER
- Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Medicine
Sammanfattning : Rheumatoid arthritis (RA) is a chronic inflammatory disease affecting peripheral joints. Persistent inflammation causes cartilage deterioration with severe joint deformations as a consequence. The etiology is largely unknown but complex interactions between genetic and environmental factors contribute to the disease. LÄS MER
- Detta är en avhandling från Stockholm : Karolinska Institutet, Dept of Medical Biochemistry and Biophysics
Sammanfattning : Unravelling the genetic susceptibility to complex autoimmune diseases and understanding these pathologies on a mechanistic level are major obstacles to improve our possibilities for therapeutic intervention and an increase in the quality of life of affected patients. Studies in experimental rodent models, that can be run under stable environmental conditions, which itself can be subjected to experimental manipulation, and in cohorts of potentially unlimited size, hold significant promise for the understanding of genes and pathways involved in complex autoimmune diseases. LÄS MER
- Detta är en avhandling från Center for Molecular Biomedicine, Lund University
Sammanfattning : The immune pathology and MHC association of chronic arthritis was studied in three rat models for reumatoid arthritis (RA). Susceptible rat strains develop a T cell dependent chronic disease after immunization with rat collagen type II (CII). LÄS MER