Sökning: "QTL Analysis"

Visar resultat 6 - 10 av 52 avhandlingar innehållade orden QTL Analysis.

1. 6. An e-Science Approach to Genetic Analysis of Quantitative Traits

   Författare :Mahen Jayawardena; Sverker Holmgren; Erwin Laure; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; QTL Analysis; Grid Computing; Global Optimization; e-Science; Beräkningsvetenskap; Scientific Computing;

   Sammanfattning : Many important traits in plants, animals and humans are quantitative, and most such traits are generally believed to be affected by multiple genetic loci. Standard computational tools for mapping of quantitative traits (i.e. LÄS MER

3. 7. The Complex Genetics behind Neurodegeneration and Susceptibility to Parkinson’s disease

   Författare :Michael Jewett; Translationell Neurogenetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson’s Disease; α-synuclein; Dopaminergic Neurons; Susceptibility; GSTA4; Vra1; rAAV; 6-OHDA; En1; Linkage analysis; Congenic strains; Axonal swellings; QTL; Risk factors; Neuroprotection; Astrocytes;

   Sammanfattning : Parkinson’s disease (PD) is the second most common neurodegenerative disorder and affects over 1% of people above the age of 65. This progressive and debilitating disease is usually thought of as a motor disease, with symptoms such as muscle rigidity, slowness of movement, and tremor at rest. LÄS MER

4. 8. Genetic analysis of autoimmune diseases using animal models : Mapping susceptibility genes for multiple sclerosis and rheumatoid arthritis

   Författare :Hai-Tao Yang; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Collagen induced arthritis CIA ; Experimental allergic encephalomyelities EAE ; Multiple sclerosis MS ; Quantitative trait loci QTL ; Rheumatoid arthritis RA ; Linkage analysis; Genetik; Clinical genetics; Klinisk genetik; Medical Genetics; medicinsk genetik;

   Sammanfattning : Autoimmune diseases such as rheumatoid arthritis and multiple sclerosis are common human diseasesaffecting 1% and 0.1% of the population respectively. These diseases are characterized by abnormal self-tolerance in the immune system and autoimmune reactions. LÄS MER

5. 9. Chicken Genomics - Linkage and QTL mapping

   Författare :Per Wahlberg; Leif Andersson; Ruedi Fries; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; chicken; quantitative genetics; linkage map; QTL mapping; recombination; long-term selection; Z chromosome; selective sweep; SNP; Genetics; Genetik;

   Sammanfattning : This thesis presents results from genetic studies conducted in the chicken (Gallus gallus). The domestication of chicken is believed to have been initiated approximately 7,000 – 9,000 years ago in Southeast Asia. LÄS MER

7. 10. Evolutionary dynamics of migration and breeding in wild birds: genetic architecture, sexual conflicts and evolutionary constraints

   Författare :Maja Tarka; Biologiska institutionen; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; quantitative genetics; heritability; intralocus sexual conflict; antagonistic selection; QTL; G-matrix; wing length; arrival date; migration; geolocator; bird; Acrocephalus arundinaceus;

   Sammanfattning : Our knowledge of the evolutionary potential of traits involved in different selective episodes, especially in natural populations, is still limited. This is true for questions such as the genetic basis and inheritance of traits, how natural and sexual selection acts on them, and how selective conflicts influence the evolutionary response to selection. LÄS MER