Sökning: "Phosphoinositides"

Visar resultat 6 - 10 av 12 avhandlingar innehållade ordet Phosphoinositides.

  1. 6. Functional characterization of cellulose and chitin synthase genes in Oomycetes

    Författare :Johanna Fugelstad; Vincent Bulone; Carol Munro; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cellulose biosynthesis; chitin biosynthesis; cellulose synthase gene; chitin synthase gene; Oomycetes; Phytophthora infestans; Saprolegnia monoica; pleckstrin homology domain; Microbiology; Mikrobiologi;

    Sammanfattning : Some species of Oomycetes are well studied pathogens that cause considerable economical losses in the agriculture and aquaculture industries. Currently, there are no chemicals available that are environmentally friendly and at the same time efficient Oomycete inhibitors. LÄS MER

  3. 7. Studies on cysteinyl leukotriene receptor 1 and 15-lipoxygenase-1 in lymphomas

    Författare :Frida Schain; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Classical Hodgkin lymphoma (cHL) is a malignant disorder with striking inflammatory features. Since cysteinyl leukotrienes (cysLTs) are potent inflammatory mediators it was of interest to study their potential role in the pathogenesis of cHL. LÄS MER

  4. 8. Lipid Signalling Dynamics in Insulin-secreting β-cells

    Författare :Anne Wuttke; Anders Tengholm; Erik Gylfe; Louis Philipson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ATP; β-cell; diacylglycerol; insulin secretion; oscillations; PtdIns 4 P; PtdIns 4; 5 P2; protein kinase C; P2Y receptor; Medical Cell Biology; Medicinsk cellbiologi;

    Sammanfattning : Certain membrane lipids are involved in intracellular signalling processes, among them phosphoinositides and diacylglycerol (DAG). They mediate a variety of functions, including the effects of nutrients and neurohormonal stimuli on insulin secretion from pancreatic β-cells. LÄS MER

  5. 9. Characterization of specific domains of the cellulose and chitin synthases from pathogenic oomycetes

    Författare :Christian Brown; Vincent Bulone; Carol Munro; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cellulose biosynthesis; chitin biosynthesis; cellulose synthase genes; chitin synthase genes; oomycetes; Saprolegnia monoica; Microtubule Interacting and Trafficking MIT domain; Pleckstrin Homology PH domain; Biotechnology; Bioteknologi;

    Sammanfattning : Some oomycetes species are severe pathogens of fish or crops. As such, they are responsible for important losses in the aquaculture industry as well as in agriculture. Saprolegnia parasitica is a major concern in aquaculture as there is currently no method available for controlling the diseases caused by this microorganism. LÄS MER

  7. 10. Regulation of docking and priming in pancreatic α- and β-cells

    Författare :Muhmmad Omar-Hmeadi; Sebastian Barg; Patrick MacDonald; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type-2 diabetes; glucagon; insulin; somatostatin; exocytosis;

    Sammanfattning : The secretion of islet hormones from endocrine cells of the pancreas plays vital roles in maintaining glucose homeostasis. Dysfunction of these cells leads to diabetes, a devastating metabolic disorder affecting millions worldwide, but underlying mechanisms remain poorly understood. LÄS MER