Sökning: "Phosphoinositides"

Visar resultat 11 - 12 av 12 avhandlingar innehållade ordet Phosphoinositides.

  1. 11. Signal transduction in the brain : modulation of receptor-mediated inositol phospholipid breakdown by potassium and fluoride ions

    Författare :Gunnar Tiger; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Inositol phospholipid breakdown; muscarinic receptors; potassium; fluoride; rat brain; pig brain;

    Sammanfattning : Neurotransmitter receptor types mediating the generation of intracellular signals are of two types; ligand-gated ion channels and G protein coupled receptors. The effector enzyme phosphoinositide-specific phospholipase C (PLC) is modulated by stimulation of G protein coupled receptors, leading to an increased breakdown of inositol phospholipids ("Ptdlns breakdown"). LÄS MER

  2. 12. Cytoskeletal mechanisms in synaptic vesicle recycling

    Författare :Jenny Gustafsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Synapse; actin cytoskeleton; synaptic vesicle; endocytosis;

    Sammanfattning : This thesis explores cytoskeletal mechanisms involved in the recycling of synaptic vesicles. As an initial step it characterizes synapses formed by giant reticulospinal axons in lamprey and defines their use as a model system. The most common type of reticulospinal synapse, "simple synapse", appeared to be most suitable as an experimental model. LÄS MER