Sökning: "PCR-RFLP"

Visar resultat 6 - 9 av 9 avhandlingar innehållade ordet PCR-RFLP.

  1. 6. Development of novel molecular methods for Campylobacter species and for Helicobacter pylori

    Författare :Kristina Blom; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Campylobacter; Helicobacter pylori; PCR; mRNA; hybridization; flow cytometry; HpaA; urease; NAP;

    Sammanfattning : Background and Aim: Different Campylobacter species and Helicobacter pylori are common causes of gastrointestinal infections that may result in diarrhea and chronic gastritis, respectively. The overall aim of this thesis was to develop novel methods for identification, differentiation and characterization of these bacteria. LÄS MER

  3. 7. Influence of genetic polymorphisms on DNA repair, p53 mutations and cancer risk

    Författare :Charlotta Ryk; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :polymorphisms; metabolism; DNA repair; p53; lung cancer; bladder cancer;

    Sammanfattning : Individuals have different susceptibility towards environmental exposures that may cause or contribute to disease. This inter-individual variation is partly due to genetic polymorphisms in genes involved in DNA repair and metabolism, which have potential to modulate the function of the encoded proteins. LÄS MER

  4. 8. Functional analysis of genetic variants in putative low penetrate breast cancer genes

    Författare :Haixin Lei; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Breast cancer; low penetrance gene; CDH1; ILC; IDC; mutation; SNP; BA CHI; ATM; EST1; cryptic splice site; SR proteins; dinucleotide repeats; splicing silencer.;

    Sammanfattning : Paper I & II: CDH1 germline mutations predispose individuals to diffuse gastric cancer, but its role in breast cancer is less clear. Somatic CDH1 mutations were reported to be frequent in lobular tumours (ILC), but they have not been found in ductal carcinomas (IDC). LÄS MER

  5. 9. Penicillin-Nonsusceptible Streptococcus pneumoniae in Malmö, Sweden. Aspects of Epidemiology, Microbiology and Genetics

    Författare :Percy Nilsson Wimar; Preventiv pediatrik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine human and vertebrates ; Day-care centers; Streptococcus pneumoniae; Penicillin-nonsusceptible; Medicin människa och djur ;

    Sammanfattning : S. pneumoniae is a major cause of common diseases such as acute otitis media and pneumonia, as well as more serious illnesses like septicemia and meningitis. The increasing level of resistance in pneumococci threatens to change the tradition of treating common respiratory infections with narrow-spectrum penicillin. LÄS MER