Sökning: "HpaA"
Visar resultat 1 - 5 av 7 avhandlingar innehållade ordet HpaA.
1. Development of novel molecular methods for Campylobacter species and for Helicobacter pylori
Sammanfattning : Background and Aim: Different Campylobacter species and Helicobacter pylori are common causes of gastrointestinal infections that may result in diarrhea and chronic gastritis, respectively. The overall aim of this thesis was to develop novel methods for identification, differentiation and characterization of these bacteria. LÄS MER
2. Experimental studies of Helicobacter pylori immunization. Identification of protective immune responses and vaccine candidate antigens
Sammanfattning : .... LÄS MER
3. Characterisation of the conserved Helicobacter pyloriproteins AhpC and HpaA
Sammanfattning : Background: Infection with Helicobacter pylori gives rise to gastritis and may cause duodenal and gastric ulcers and gastric carcinoma in humans. The infection may induce an immune response against different antigens, among them a 26 kDa protein (AhpC) and a 29 kDa protein (HpaA). Aims: The aims were to characterise the 26 kDa and 29 kDa H. LÄS MER
4. Mass spectrometry-based proteomic strategies applied to Helicobacter pylori. A Search for candidate vaccine antigens
Sammanfattning : This thesis describes the development and refinement of proteomic strategies and the application of these on the human gastric pathogen H. pylori. The purpose was to identify proteins, and in particular membrane proteins, as potential targets for vaccine development. LÄS MER
5. Studies on bacterial transmission pathways in a high endemic area, with a focus on Helicobacter pylori
Sammanfattning : Even though half of the world’s population is infected with Helicobacter pylori, which causes gastritis, peptic ulcer and gastric cancer, the transmission routes of these bacteria remain unknown despite extensive epidemiological studies. Enterotoxigenic Escherichia coli (ETEC) and Vibrio cholerae are two of the most common causes of acute watery diarrhea in developing countries. LÄS MER