Sökning: "signaling pathway"

Visar resultat 1 - 5 av 692 avhandlingar innehållade orden signaling pathway.

  1. 1. Melanophore signaling : regulation and application

    Författare :Tony P. M. Andersson; Ethan Lerner; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Melanophores are pigment-containing cells responsible for quick physiological color changes in lower vertebrates due to redistribution of melanosomes, pigment granules. We have studied melanophores from African clawed frog, Xenopus laevis. LÄS MER

  3. 2. Adrenergic signaling in insulin-sensitive tissues

    Författare :Daniel L. Yamamoto; Tore Bengtsson; Barbara Cannon; Michael Cawthorne; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Metabolism; Adrenergic; Glucose; Signaling; Skeletal muscle; Animal physiology; Zoofysiologi; zoofysiologi; Zoological physiology;

    Sammanfattning : Glucose metabolism in insulin-sensitive tissues such as skeletal muscle and adipose tissue is tightly regulated by external stimuli. Metabolic changes in these tissues have direct effects on whole body metabolism. Such metabolic changes can be induced or influenced by adrenergic stimulation. LÄS MER

  4. 3. Bone and Cartilage Regeneration: Wnt Signaling Pathway in Healing

    Författare :Anna Thorfve; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Wnt signaling pathway; Osteoarthritis; Bone regeneration; Lithium;

    Sammanfattning : The Wnt signaling pathway plays a central role in bone and cartilage embryonic development, processes that are recapitulated during regeneration. Imbalance in such well conserved and complex system often contributes to numerous diseases, whereas controlled modulation of the Wnt signaling activity is an attractive target e.g. LÄS MER

  5. 4. Regulation of hematopoiesis by the Smad signaling pathway

    Författare :Ulrika Blank Savukinas; Avdelningen för molekylärmedicin och genterapi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine human and vertebrates ; retroviral mediated gene expression; conditional knockout; hematopoietic stem cell; hematopoiesis; Transforming growth factor-beta; Smad signaling; Medicin människa och djur ;

    Sammanfattning : Hematopoietic stem cells (HSCs) reside in the bone marrow (BM) of adult individuals and are ultimately responsible for the continuous production of blood cells throughout life. The regulation of HSCs in vivo is tightly regulated by both intrinsic and extrinsic factors. LÄS MER

  7. 5. Global functional association network inference and crosstalk analysis for pathway annotation

    Författare :Christoph Ogris; Erik Sonnhammer; Alfonso Valencia; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; biological networks; genome wide functional association networks; global gene association networks; gene networks; protein networks; functional association; functional coupling; network biology pathway analysis; pathway annotation; pathway enrichment; network-based enrichment; enrichment; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

    Sammanfattning : Cell functions are steered by complex interactions of gene products, like forming a temporary or stable complex, altering gene expression or catalyzing a reaction. Mapping these interactions is the key in understanding biological processes and therefore is the focus of numerous experiments and studies. LÄS MER