Sökning: "rhodopsin"

Visar resultat 1 - 5 av 28 avhandlingar innehållade ordet rhodopsin.

1. 1. Time Resolved Diffraction Studies of Structural Changes in Sensory Rhodopsin

   Författare :Robert Bosman; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Rhodopsin; SRII; SRII-HtrII; Time-resolved crystallography; Time-resolved wide angle x-ray scattering; TR-X; TR-WAXS; Serial crystallography;

   Sammanfattning : Responding to different light conditions is an essential process for many organisms on earth. Unicellular organisms are no exception to this and mechanisms for controlling cellular movement must often be sensitive to light. LÄS MER

3. 2. Phenotypes and genotypes in families with hereditary tapetoretinal degenerations

   Författare :Vesna Ponjavic; Lund Oftalmologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; peripherin.; rhodopsin; cone-rod dystrophy; retinitis pigmentosa; choroideremia; central areolar choroidal dystrophy; mutation screening; full-field electroretinography; Phenotype; genotype; Ophtalmology; Oftalmologi;

   Sammanfattning : The purpose of the study was to characterise the phenotype with emphasis on electroretinography in four different types of hereditary retinal degeneration and to correlate it to a genotype when possible. Two methods were used: full-field electroretinography for objective assessment of retinal function and mutation screening of blood samples for detection of gene alterations. LÄS MER

4. 3. Shedding light on retinal. A contribution to the understanding of the primary process of vision

   Författare :Fredrik Blomgren; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; retinal; rhodopsin; quantum mechanics molecular mechanics; calculations; ab initio;

   Sammanfattning : In our eyes light is absorbed by a polyene molecule called retinal. This molecule contains six double bonds and is bonded to a protein. The protein-chromophore complex is called rhodopsin and has been structurally determined by crystallography. It was early suggested that the main event in vision is a cis-trans isomerization of retinal. LÄS MER

5. 4. Identification, Characterization and Evolution of Membrane-bound Proteins

   Författare :Pär J. Höglund; Helgi B. Schiöth; Robert Fredriksson; Gert Vriend; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; G protein-coupled receptor; GPCR; Solute Carriers; SLC; Bioinformatics; Evolution; Rhodopsin; Adhesion; Phylogeny; Pharmacology; Farmakologi;

   Sammanfattning : Membrane proteins constitute approximately 30% of all genes in the human genome and two large families of membrane proteins are G protein-coupled receptors (GPCRs) and Solute Carriers (SLCs) with about 800 and 380 human genes, respectively.In Papers I, II and IV, we report 16 novel human Adhesion GPCRs found by searches in NCBI and Celera databases. LÄS MER

7. 5. Characterization and Evolution of Transmembrane Proteins with Focus on G-protein coupled receptors in Pre-vertebrate Species

   Författare :Karl J. V. Nordström; Helgi B. Schiöth; Robert Fredriksson; Teresa Attwood; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; G protein-coupled receptors; GPCR; Membrane protein; Rhodopsin; Adhesion; Secretin; Evolution; Bioinformatics; Phylogeny; Pharmacological research; Farmakologisk forskning; Bioinformatics; Bioinformatik; Bioinformatik; Bioinformatics; Biology with specialization in Molecular Evolution; Biologi med inriktning mot molekylär evolution;

   Sammanfattning : G protein-coupled receptors (GPCRs) are one of the largest protein families in mammals. GPCRs are instrumental for hormonal and neurotransmitter signalling and are important in all major physiological systems of the body. LÄS MER