Sökning: "MEDICIN B12"

Visar resultat 1 - 5 av 28 avhandlingar innehållade orden MEDICIN B12.

  1. 1. Vascular mechanisms in dementia with special reference to folate and fibrinolysis

    Författare :Nils-Olof Hagnelius; Torbjörn K. Nilsson; Teodoro Bottiglieri; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dementia; Alzheimer’s disease; vascular dementia; folate; homocysteine; vitamin B12; CSF Serum folate ratio; fibrinolysis; tPA; PAI-1; Geriatrics and medical gerontology; Geriatrik och medicinsk gerontologi; MEDICINE; MEDICIN; Geriatrik; Geriatrics; Medicin; Medicine;

    Sammanfattning : The aim of this thesis was to study the biomarker homocysteine and other novel potential vascular risk factors for dementia. In an out-patient based study of a cohort of 926 consecutive subjects referred to our Memory Unit during 1996―2000, serum-folate was lower and total plasma homocysteine (tHcy) and serum methyl malonate were higher in subjects being prescribed with B12. LÄS MER

  3. 2. Cobalamin communication in Sweden 1990 – 2000 : views, knowledge and practice among Swedish physicians

    Författare :Mats Nilsson; Johan Lökk; Göran Westman; Bo Norberg; Kurt Svärdsudd; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Cobalamin; folate; iron; homocysteine; MMA; vitamin B12 deficiency; therapy tradition; drug epidemiology; communication; receivers; senders; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; medicin; Medicine;

    Sammanfattning : Cobalamin (vitamin B12) is one of several essential micronutrients needed by the human organism. Other important micronutritients, which interplay with vitamin B12, are folate and iron. During the last ten years, the attention has been drawn to different forms of neurological disorders supposed to be caused by vitamin B12 deficiency. LÄS MER

  4. 3. Vitamin B12 and folate depletion in the elderly. Diagnosis, clinical correlates and causes

    Författare :Catharina Lewerin; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; aged; methylmalonic acid; homocysteine; vitamin B12; folic acid; renal function; cognition; movement; atrophic gastritis;

    Sammanfattning : Subclinical vitamin B12 and folate deficiency is common in the elderly. The clinical significance remains unresolved. There is not a universally accepted set of laboratory criteria for diagnosis, however subclinical deficiency is important to diagnose since it is easy to treat. LÄS MER

  5. 4. Studies of Autoantibodies in Systemic and Organ-Specific Autoimmune Disease

    Författare :Filip Sköldberg; Olle Kämpe; Fredrik Rorsman; Lars Rönnblom; Eva Landgren; Marie Wahren-Herlenius; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; autoantibodies; autoimmune polyendocrine syndrome type 1; cysteine sulfinic acid decarboxylase; histidine decarboxylase; systemic lupus erythematosus; ahnak; CLLD4; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; Molekylär medicin; Molecular Medicine;

    Sammanfattning : Systemic lupus erythematosus (SLE) is the prototypic systemic autoimmune disease, whereas autoimmune polyendocrine syndrome type 1 (APS1) is a rare autosomal disorder characterized by combinations of organ-specific autoimmune manifestations including hypoparathyroidism and intestinal dysfunction, and may serve as a model for organ-specific autoimmunity. Autoantibodies directed against proteins expressed in the affected tissues are found in both diseases. LÄS MER

  7. 5. Studies on Vitamin B12 and Folate Deficiency Markers in the Elderly : A Population-based Study

    Författare :Karin Björkegren; Kurt Svärdsudd; Åke Schwan; Herman Nilsson-Ehle; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Cobalamin; folate; MMA; tHcy; multivitamin; symptoms; survey; treatment trial; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; Family Medicine; Allmänmedicin;

    Sammanfattning : The aims of this study were to document the levels of cobalamin, folate, methylmalonic acid (MMA) and total homocysteine (tHcy) in serum and their relations to symptoms, clinical findings, and other factors in order to improve the possibilities of detecting early deficiency of vitamin B12 or folate, and to study the effects of cobalamin and folic acid treatment over a three-year period. The study population consisted of a 20% random sample of persons 70 years or older living in Älvkarleby in mid-Sweden. LÄS MER