Sökning: "Lars Hellman"

Visar resultat 11 - 15 av 15 avhandlingar innehållade orden Lars Hellman.

  1. 11. Characterization of secreted Giardia intestinalis cysteine proteases

    Författare :Jingyi Liu; Staffan G Svärd; Lars Hellman; Andre Buret; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Giardia intestinalis; ESPs; CPs; apical junction; chemokines; phage display; immunoglobulins; defensins; mucin.; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

    Sammanfattning : Giardia intestinalis, the causative agent of the diarrheal disease giardiasis, is a protozoan parasite that colonizes the upper small intestine of mammals, including humans. It can be divided into eight genotypes or assemblages (A through H) and only assemblage A and B are infective to humans. LÄS MER

  3. 12. Three Subfamilies of KRAB Zinc Finger Proteins : A Structural, Functional and Evolutionary Analysis

    Författare :Charlotta Mark; Lars Hellman; Fredrik Öberg; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biology; Krüppel zinc finger; KRAB; TIF1β; transcriptional repression; Biologi; Biology; Biologi; Molecular Immunology; molekylär immunologi;

    Sammanfattning : Krüppel-related zinc finger proteins constitute the largest single class of transcription factors within the human genome. Members of this protein family have the ability to either activate or repress transcription depending on the presence of specific activator or repressor domains within the protein. LÄS MER

  4. 13. Hematopoietic Serine Proteases from the Mast Cell Chymase and Tryptase Loci - a Functional and Evolutionary Analysis

    Författare :Jenny Reimer; Lars Hellman; Gunnar Nilsson; Sara Wernersson; Göran Andersson; Uppsala universitet; []
    Nyckelord :Cell and molecular biology; immune system; mast cell; basophil; mast cell chymase locus; multigene tryptase locus; serine protease; evolution; Cell- och molekylärbiologi;

    Sammanfattning : Mast cells are key effector cells in allergic and inflammatory diseases. However, their primary role is most likely in host defence against parasitic and bacterial infections. Mast cells are a particularly rich source of serine proteases. LÄS MER

  5. 14. Haematopoietic Serine Proteases : A Cleavage Specificity Analysis

    Författare :Michael Thorpe; Lars Hellman; Urban Gullberg; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mast cell; cleavage specificity; phage display; chymase; serine protease; granzyme; fish protease;

    Sammanfattning : Mast cells are innate immune cells, historically involved in allergy responses involving IgE. Through this, they have earned a reputation as a fairly detrimental cell type. Their beneficial roles remain somewhat enigmatic although they clearly have the ability to modulate the immune system. LÄS MER

  7. 15. Epidemiological Studies of Small Intestinal Tumours

    Författare :Niklas Zar; Per Hellman; Lars Holmberg; Jonas Rastad; Anders Bergenfelz; Uppsala universitet; []
    Nyckelord :Surgery; small intestine; adenocarcinoma; carcinoid; epidemiology; survival; second malignancies; causes of death; Crohn s disease; Kirurgi;

    Sammanfattning : Malignant tumours of the small intestine are rare. Age-standardised incidence in Europe is between 0.5-1.5 per 100 000. LÄS MER