Sökning: "apical junction"

Visar resultat 1 - 5 av 13 avhandlingar innehållade orden apical junction.

1. 1. Characterization of secreted Giardia intestinalis cysteine proteases

   Författare :Jingyi Liu; Staffan G Svärd; Lars Hellman; Andre Buret; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Giardia intestinalis; ESPs; CPs; apical junction; chemokines; phage display; immunoglobulins; defensins; mucin.; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

   Sammanfattning : Giardia intestinalis, the causative agent of the diarrheal disease giardiasis, is a protozoan parasite that colonizes the upper small intestine of mammals, including humans. It can be divided into eight genotypes or assemblages (A through H) and only assemblage A and B are infective to humans. LÄS MER

3. 2. In vitro studies on the mechanisms of inhibited thyroidal iodide uptake and destructive thyroiditis as adverse effects of amiodarone and interferon-gamma

   Författare :Sofia Tedelind; Göteborgs universitet; []
   Nyckelord :thyroid; amiodarone; interferon-gamma; iodide transport; tight junction; mitochondria; endocytosis;

   Sammanfattning : The clinical use of the potent anti-arrhythmic drug amiodarone is limited due to adverse effects e.g. in the thyroid comprising both hypo- and hyperthyroidism. Amiodarone-induced thyroid dysfunction can occur in subjects with normal thyroid glands but also in those with an underlying thyroid abnormality resulting in an aggravation of the condition. LÄS MER

4. 3. New roles for apical secretion and extracellular matrix assembly in Drosophila epithelial morphogenesis

   Författare :Satish Arcot Jayaram; Christos Samakovlis; Catherine Rabouille; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Utvecklingsbiologi; utvecklingsbiologi; Developmental Biology;

   Sammanfattning : Branched tubular organs, such as the lung and vascular system fulfill the respiratory needs of most animals. Optimal tissue function relies on the uniform sizes and shapes of the constituting branches in each organ. LÄS MER

5. 4. New Approaches to Studies of Paracellular Drug Transport in Intestinal Epithelial Cell Monolayers

   Författare :Staffan Tavelin; Per Artursson; Staffan Tavelin; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; intestinal epithelium; tight junctions; cell culture; Galenisk farmaci; Pharmaceutics; Galenisk farmaci; galenisk farmaci; Pharmaceutics;

   Sammanfattning : Studies of intestinal drug permeability have traditionally been performed in the colon-derived Caco-2 cell model. However, the permeability of these cell monolayers resembles that of the colon rather than that of the small intestine, which is the major site of drug absorption following oral administration. LÄS MER

7. 5. Protein kinase C-dependent regulation of the epithelial barrier

   Författare :Anita Sjö; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : The intestinal epithelium is essential for the absorption of nutrients and for the defence against harmful substances in the gut. The permeability and barrier functions of epithelia are mainly controlled by the intercellular tight junctions. LÄS MER