Sökning: "Human genome"

Visar resultat 41 - 45 av 683 avhandlingar innehållade orden Human genome.

  1. 41. Characterizing the spectrum of somatic alterations in canine and human cancers

    Författare :Sharadha Sakthikumar; Kerstin Lindblad-Toh; Richard Rosenquist Brandell; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dog; osteosarcoma; hemangiosarcoma; glioblastoma; non-coding; whole-exome; whole-genome; sequencing; bioinformatics; comparative genetics.;

    Sammanfattning : Cancers arise as a result of deleterious somatic alterations accumulating in the genome during the process of cell division. These alterations arise either via exposure to mutagens or due to errors occurring during DNA replication. LÄS MER

  2. 42. Analysis of Nucleotide Variations in Non-human Primates

    Författare :Ann-Charlotte Rönn; Ann-Christine Syvänen; Mats Nilsson; Phillip Morin; Uppsala universitet; []
    Nyckelord :Molecular genetics; SNP; genotyping; primate; chimpanzee; whole genome amplification; multiple displacement amplification; minisequencing; microarray; Y-chromosome; mitochondria; Genetik;

    Sammanfattning : Many of our closest relatives, the primates, are endangered and could be extinct in a near future. To increase the knowledge of non-human primate genomes, and at the same time acquire information on our own genomic evolution, studies using high-throughput technologies are applied, which raises the demand for large amounts of high quality DNA. LÄS MER

  3. 43. Human mouse mammary tumor virus like elements and their relations to breast cancer

    Författare :Hong Yin; Uppsala universitet; []
    Nyckelord :Medical sciences; human MMTV like sequence HML ; human breast cancer; expression of HML; integration of HML sequence; localization of HML-6; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; mikrobiologi; Microbiology;

    Sammanfattning : The human genome contains a variety of more or less ancient endogenous retroviral sequences. They are commonly referred to as HERVs (human endogenous retroviruses). Of all the known HERV groups, the HERV-K supergroup apparently comes closest to encoding functional retroviral proteins, although infectious particles have not been demonstrated. LÄS MER

  4. 44. Inter and Intra-Assemblage Characterizations of Giardia intestinalis: from clinic to genome

    Författare :Johan Ankarklev; Staffan Svärd; Johanna P. Daily; Uppsala universitet; []
    Nyckelord :Giardia; protozoa; parasite infection; diarrhea; genome sequencing; comparative genomics; genotyping; ASH; MLG; Infektionssjukdomar; Infectious Diseases; Molekylär medicin; Molecular Medicine; Mikrobiologi; Microbiology;

    Sammanfattning : The protozoan parasite Giardia intestinalis (syn. G. lamblia, G. duodenalis) is one of the most common causes of diarrheal disease throughout the world, where an estimated 500 million people are infected annually. LÄS MER

  5. 45. Evolution and Pharmacology of Neuropeptide Y Receptors, Implications for vertebrate genome duplications

    Författare :Robert Fredriksson; Susanne Holmgren; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Evolution; tetraploidizations; G-protein coupled receptor; neuropeptide Y; zebrafish; chicken; rainbow trout; lamprey; genome duplications; peptide YY; pancreatic polypeptide; Neurovetenskap; Neurology; Neurologi; medicinsk farmakologi; Medical Pharmacology;

    Sammanfattning : The Y receptors comprise a family of evolutionarily related receptors belonging to the superfamily of G-protein coupled receptors (GPCR). Their natural ligands are in mammals neuropeptide Y (NPY), peptide YY (PYY) and pancreatic polypeptide (PP). LÄS MER