Sökning: "Human genome"
Visar resultat 21 - 25 av 682 avhandlingar innehållade orden Human genome.
21. Detection of human papillomavirus : a study of normal cells, cervical intraepithelial neoplasia and cancer of the uterine cervix
Sammanfattning : Human papillomavirus (HPV) infections of the genital tract are now recognized to be among the most prevalent sexually transmitted diseases and also a contributing factor to some cancers of the lower genital tract of women and men. Presence of HPV in a clinical specimen is confined to detection of the HPV genome by DNA hybridization techniques. LÄS MER
22. Genome-Wide Studies of Transcriptional Regulation in Human Liver Cells by High-throughput Sequencing
Sammanfattning : The human genome contains slightly more than 20 000 genes that are expressed in a tissue specific manner. Transcription factors play a key role in gene regulation. By mapping the transcription factor binding sites genome-wide we can understand their role in different biological processes. LÄS MER
23. The genetics of systemic lupus erythematosus : Mapping of susceptibility loci for human SLE
Sammanfattning : Systemic lupus erythematosus (SLE) is a systemic autoimmune disease affecting organs such as skin, jointsand kidneys. Characteristic for the disease is increased production of autoantibodies, in particular against dsDNA. Previous studies of SLE in mouse models and in humans indicate polygenic inheritance and genetic heterogeneity. LÄS MER
24. Lifestyle and Genome Evolution in Vector-Borne Bacteria : A Comparison of Three Bartonella Species
Sammanfattning : Bacterial genomes provide records of the molecular processes associated with emergence and evolution of different bacterial lifestyles. This thesis is based on whole-genome comparisons within the genus Bartonella, an excellent model system for studies of host- and vector-specificity and infection outcome in animal-associated bacteria. LÄS MER
25. Population Genetic Methods and Applications to Human Genomes
Sammanfattning : Population Genetics has led to countless numbers of fruitful studies of evolution, due to its abilities for prediction and description of the most important evolutionary processes such as mutation, genetic drift and selection. The field is still growing today, with new methods and models being developed to answer questions of evolutionary relevance and to lift the veil on the past of all life forms. LÄS MER