Sökning: "Glycosylation"

Visar resultat 26 - 30 av 193 avhandlingar innehållade ordet Glycosylation.

  1. 26. Synthesis of Orthogonally Functionalized Oligosaccharides for Self-assembled Monolayers and as Multimodal Tools in Chemical Biology

    Författare :Timmy Fyrner; Peter Konradsson; Stefan Svensson; Bo Liedberg; Ulf Ellervik; Linköpings universitet; []
    Nyckelord :Oligosaccharide synthesis; glycosylation; thioglycosides; orthogonally protected; oligo lactosides ; spacer molecule; heterobifunctional; surface plasmon resonance; lipid anchor; self-assembled monolayers; glyconanoparticles;

    Sammanfattning : This thesis covers different topics in the field of synthetic organic chemistry combined with the field of surface science and glycobiology.First, the text presents a series of orthogonally protected oligosaccharides (tri-, penta-, and heptasaccharides) of varying length and structures, which are synthesized with the aim of developing novel heterobifunctional biocompatible cross-linkers. LÄS MER

  3. 27. Structural and functional analyses of infectious pancreatic necrosis virus (IPNV)

    Författare :Anna Hjalmarsson; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cellular localisation; glycosylation; VP3-RNA cores; virus-specified components; immuno dot blot; TCID50; IPNV; purification; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Sammanfattning : Infectious pancreatic necrosis virus (IPNV) is a naked virus of an uncomplicated structure. In the interior part of the virion, the two segments of double-stranded RNA are located together with the minor structural protein VP1. This protein is detected in its free form as well as linked to the genome. LÄS MER

  4. 28. Multimodal Interaction Chromatography for the Investigation and Separation of Proteins

    Författare :Kristian Kallberg; Tillämpad biokemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Hydrophobic interaction chromatography; Multimodal chromatography; Glycosylation; Antibody; Hemoglobin; Protein purification.;

    Sammanfattning : Minor structural changes on the surface of proteins can have tremendous impact on their biological properties. When producing therapeutic proteins it is therefore important to verify that the generated protein is the desired one. LÄS MER

  5. 29. Genetic and serologic characterization of a Swedish human hantavirus isolate

    Författare :Marie Lindkvist; Göran Bucht; Clas Alhm; Per Juto; Rainer Ulrich; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hantavirus; puumalavirus; diagnostics; HFRS; nucleocapsid protein; B-cell epitopes; epitope-mapping; protein interactions; glycosylation; antibody response; cross-reactivity; Virology; Virologi;

    Sammanfattning : Hantaviruses are found practically all over the world and cause hemorrhagic fevers in man. Each year about 150,000 people are hospitalized in these zoonotic infections which can be of two types: hemorrhagic fever with renal syndrome (HFRS) or hantavirus cardiopulmonary syndrome (HCPS), depending on the infecting virus. LÄS MER

  7. 30. Development of a Novel Promoter System for Thioglycoside Activation; and its application in the synthesis of a GD3 bis-lactam

    Författare :Andréas Meijer; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; GD3; Organic chemistry; bis-lactam; ganglioside; thioglycoside; promoter; iodine monobromide; glycosylation; iodine monochloride; Organisk kemi;

    Sammanfattning : A novel promoter system IX/AgOTf (X=Cl or Br) for thioglycoside activation has been developed (paper I-II). The promoter system has been evaluated in the synthesis of two GD3 bis-lactam fragments (paper III)... LÄS MER