Sökning: "Glycosylation"

Visar resultat 11 - 15 av 175 avhandlingar innehållade ordet Glycosylation.

  1. 11. Separation of Glycoproteins using Shielding Boronate Affinity Chromatography

    Detta är en avhandling från Biotechnology, Lund University

    Författare :YuCai Li; [2001]
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; affinity chromatography; boronate; chymotrypsin; haemoglobin; mistletoe lectin; neoglycoprotein; glycosylation; shielding; Biotechnology; Bioteknik; Pharmaceutical and related technologies; Läkemedelsteknik och relaterad teknik;

    Sammanfattning : Glycoproteins, a class of biomolecules, exhibit a variety of biological activities and therefore are of importance in modern biotechnology and pharmaceutical industry. Pure glycoproteins are needed for structural and functional studies. However, the separation of glycoproteins has been a problem until now due to their structural complexity. LÄS MER

  2. 12. Helicobacter spp. – host interaction in the mucus niche

    Detta är en avhandling från Göteborgs universitet

    Författare :Médea Padra; Göteborgs universitet.; Gothenburg University.; [2018]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Helicobacter; mucin; glycosylation; adhesion;

    Sammanfattning : Helicobacter pylori is the most common human gastric pathogen, colonizing half of the world's population. Helicobacter suis colonizes the stomach of 60-95% of pigs at slaughter age and it is the most prevalent non-Helicobacter pylori Helicobacter species found in the human stomach causing severe gastric disorders. LÄS MER

  3. 13. Intrapatient evolution of HIV-1 in the context of coreceptor usage

    Detta är en avhandling från Lund University, Faculty of Medicine Doctoral Dissertation Series

    Författare :Mattias Mild; Lund University.; Lunds universitet.; [2007]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; coreceptor switch; Medicine human and vertebrates ; Medicin människa och djur ; biological cloning; R5-X4; coreceptor usage; glycosylation; recombination; HIV; evolution;

    Sammanfattning : The variable region 1 to 3 (V1-V3) of the HIV-1 envelope plays an important role in coreceptor usage. Early in infection HIV- 1 is using CCR5 as coreceptor to enter target cells (R5 viruses) whereas viruses using CXCR4 as coreceptor (X4 viruses) may appear later in infection. LÄS MER

  4. 14. Clusterin in brain and cerebrospinal fluidin Alzheimer s disease

    Detta är en avhandling från Lund University, Faculty of Medicine Doctoral Dissertation Series

    Författare :Anna-Maria Nilselid; Göteborgs universitet.; Gothenburg University.; [2005]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer s disease; clusterin; apolipoprotein J; SP-40; brain tissue; cerebrospinal fluid; glycosylation; biomarker; enzyme-linked immunosorbent assay;

    Sammanfattning : The apolipoprotein clusterin is suggested to be involved in the pathogenesis of Alzheimer¡¦s disease (AD). At the start of these studies, results had indicated that clusterin was elevated in AD brain, compared with controls. LÄS MER

  5. 15. Development and Application of Proximity Assays for Proteome Analysis in Medicine

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Felipe Marques Souza de Oliveira; Uppsala universitet.; [2018]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Solid-phase proximity ligation assay; post-translational modifications; glycosylation; phosphorylation; Enzyme-linked immunosorbent assay; immunoassay and rolling circle amplification; Proximity Extension Assay; inflammation protein biomarkers; autoantibodies; autoimmune disease;

    Sammanfattning : Along with proteins, a myriad of different molecular biomarkers, such as post-translational modifications and autoantibodies, could be used in an attempt to improve disease detection and progression. In this thesis, I build on several iterations of the proximity ligation assay to develop and apply new adaptable methods to facilitate detection of proteins, autoantibodies and post-translational modifications. LÄS MER