Sökning: "glyconanoparticles"

Hittade 2 avhandlingar innehållade ordet glyconanoparticles.

  1. 1. Synthesis of Orthogonally Functionalized Oligosaccharides for Self-assembled Monolayers and as Multimodal Tools in Chemical Biology

    Författare :Timmy Fyrner; Peter Konradsson; Stefan Svensson; Bo Liedberg; Ulf Ellervik; Linköpings universitet; []
    Nyckelord :Oligosaccharide synthesis; glycosylation; thioglycosides; orthogonally protected; oligo lactosides ; spacer molecule; heterobifunctional; surface plasmon resonance; lipid anchor; self-assembled monolayers; glyconanoparticles;

    Sammanfattning : This thesis covers different topics in the field of synthetic organic chemistry combined with the field of surface science and glycobiology.First, the text presents a series of orthogonally protected oligosaccharides (tri-, penta-, and heptasaccharides) of varying length and structures, which are synthesized with the aim of developing novel heterobifunctional biocompatible cross-linkers. LÄS MER

  3. 2. Carbohydrate-Functionalized Nanomaterials : Synthesis, Characterization and Biorecognition Studies

    Författare :Na Kong; Mingdi Yan; Joseph J. Barchi Jr; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; carbohydrate; glyconanomaterials; perfluorophenyl azide PFPA ; CuAAC; AAAC; coupling chemistry; 19 F q NMR; lectin; carbon nanomaterials; microwave irradiation; Kemi; Chemistry; Bioteknologi; Biotechnology;

    Sammanfattning : This thesis focuses on the development of carbohydrate coupling chemistry on nanomaterials and their biological activity studies. It is divided into two parts:In part one, two carbohydrate immobilization approaches, based on perfluorophenyl azide (PFPA)-functionalized silica nanoparticles (SNPs), are presented, where the binding affinity of the glyconanoparticles was evaluated through carbohydrate-lectin interaction. LÄS MER