Sökning: "nucleocapsid protein"

Visar resultat 1 - 5 av 20 avhandlingar innehållade orden nucleocapsid protein.

  1. 1. Genetic and serologic characterization of a Swedish human hantavirus isolate

    Författare :Marie Lindkvist; Göran Bucht; Clas Alhm; Per Juto; Rainer Ulrich; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hantavirus; puumalavirus; diagnostics; HFRS; nucleocapsid protein; B-cell epitopes; epitope-mapping; protein interactions; glycosylation; antibody response; cross-reactivity; Virology; Virologi;

    Sammanfattning : Hantaviruses are found practically all over the world and cause hemorrhagic fevers in man. Each year about 150,000 people are hospitalized in these zoonotic infections which can be of two types: hemorrhagic fever with renal syndrome (HFRS) or hantavirus cardiopulmonary syndrome (HCPS), depending on the infecting virus. LÄS MER

  2. 2. Protein interactions involved in alphavirus assembly

    Författare :Ulrica Skoging Nyberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Alphavirus; Semliki Forest Virus; Virus assembly; Capsid Protein; Nucleocapsid; Viral Envelope Proteins;

    Sammanfattning : Viruses have to protect their genomes during transport from the infected to an uninfected host cell. This is achieved by forming a protein shell around the nucleic acid. Virus assembly is a complex process that involves interactions with the viral genome, the viral structural proteins and for enveloped viruses a lipid membrane. LÄS MER

  3. 3. Viral dUTPases, Recombinant Expression, Purification and Characterization

    Författare :Anna-Carin Bergman; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Proteins; nucleocapsid protein; retrovirus; herpesvirus; dUTPase; nucleotide metabolism; enzymology; Proteiner; enzymologi;

    Sammanfattning : The enzyme deoxyuridine 5’-triphosphate nucleotidohydrolase (dUTPase, EC 3.6.1.23) catalyzes the hydrolysis of dUTP to dUMP and pyrophosphate. LÄS MER

  4. 4. The role of the capsid protein in Semliki Forest virus assembly

    Författare :Kerstin Forsell; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Semliki Forest virus; RNA encapsidation; NC assembly; virus budding; RNA uncoating;

    Sammanfattning : Enveloped viruses, like the Alphaviruses, encapsidate their genomes into a nucleocapsid (NC) or core structure which is surrounded by a lipid bilayer (envelope) with spike proteins. The alphavirus Semliki Forest virus (SFV), is an RNA virus with a genomic 42 S RNA of positive polarity. LÄS MER

  5. 5. Assembly and entry mechanisms of Semliki Forest virus

    Författare :Bernd Uwe Barth; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Semliki Forest virus; virus assembly; protein oligomerization; virus budding;

    Sammanfattning : The genomes of enveloped viruses are packaged into a core or nucleocapsid (NC) which is surrounded by a lipid membrane with spike proteins. These viruses mature by budding at a membrane of the host cell, usually the plasma membrane (PM), and penetrate into new ones by a virus-host membrane fusion event. LÄS MER