Sökning: "Gene Fusion"

Visar resultat 21 - 25 av 222 avhandlingar innehållade orden Gene Fusion.

  1. 21. Molecular studies of genetic changes in myxoid and round cell liposarcoma

    Författare :Sofia Järnum; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancerology; Cytologi; onkologi; cancer; Medicine human and vertebrates ; Medicin människa och djur ; oncology; Cytology; autocrine loop; RDA; persephin; RET; LEPREL1; translocation; fusion gene; liposarcoma; TLS; CHOP;

    Sammanfattning : Chromosomal translocations commonly result in the production of fusion genes and the fusion genes are often tumor-type specific. In myxoid and round cell liposarcomas (MLS/RCLS), almost 95% of the cases carry a t(12;16)(q13;p11). In the remaining 5% of the MLS/RCLS tumors, another translocation and fusion gene can be found, i.e. LÄS MER

  3. 22. Genetically Engineered Plants: Improved stress tolerance, growth and facilitated protein purification

    Författare :Gösta Lilius; Tillämpad biokemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; glycine betaine; gene; freezing; flooding; drought; dicoteledones; desiccation; compatible solutes; cold; choline dehydrogenase; chill; CDH; betaine; betA; alkaloids anoxia; affinity purification; affinity tags; handles; hemoglobin; hypoxia; low temperatu; Biotechnology; Bioteknik;

    Sammanfattning : Heterologous genes were expressed in plants in which the overall goal was to increase the value of the final crop. Various aspects were explored and evaluated, such as improving the stress tolerance, enhancing the availability of oxygen in growing cells and producing rare proteins with increased degrees of purity. LÄS MER

  4. 23. Spatially Resolved Gene Expression Analysis

    Författare :Michaela Asp; Joakim Lundeberg; Patrik Ståhl; Thierry Voet; KTH; []
    Nyckelord :RNA; RNA-sequencing; transcriptomics; spatial transcriptomics; single cells; Bioteknologi; Biotechnology;

    Sammanfattning : Spatially resolved transcriptomics has greatly expanded our knowledge of complex multicellular biological systems. To date, several technologies have been developed that combine gene expression data with information about its spatial tissue context. LÄS MER

  5. 24. Image analysis of prostate cancer tissue biomarkers

    Författare :Giuseppe Lippolis; Malmö Urologisk cancerforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostate cancer; image analysis; Time Resolved Fluorescence; automated Gleason; PSA; AR; fusion gene; TMAs;

    Sammanfattning : Prostate cancer is the second most common cancer in men. In order to improve diagnosis and prognosis, new sensitive and specific biomarkers are needed. Tissue biomarkers carry expression and morphological information of the tissue where they are expressed. LÄS MER

  7. 25. Strategies for functionalization of recombinant spider silk

    Författare :Ronnie Jansson; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; spider silk; functionalization; gene fusion; affinity domain; IgG; biomolecule presentation; enzyme immobilization; conductivity; Pichia pastoris; Bioteknologi; Biotechnology;

    Sammanfattning : .... LÄS MER