Sökning: "RNA-sequencing"
Visar resultat 1 - 5 av 270 avhandlingar innehållade ordet RNA-sequencing.
1. RNA Sequencing for Molecular Diagnostics in Breast Cancer
Sammanfattning : Breast cancer is the most common type of cancer in women and, in Sweden, is the most deadly second only to lung cancer. While treatment and diagnostic options have improved in the past decades and short- to mid-term survival is good, long-term survival is much poorer. LÄS MER
2. Breast Cancer Biomarkers with Clinical Relevance Identified by Massively-parallel DNA and RNA Sequencing
Sammanfattning : Women have a 10% lifetime risk of developing breast cancer, and the disease has surpassed lung cancer as the most frequently diagnosed type of cancer in the world. Breast cancer originates in the epithelial cells of the mammary gland and tumor cells have undergone a series of genetic and phenotypic changes that confer tumor promoting properties. LÄS MER
3. Single-cell RNA sequencing as a tool to study panarthropod evolution
Sammanfattning : Panarthropoda is a monophyletic group comprised of arthropods and lobopods, molting animals with a segmented body, paired appendages, dorsal brain, and ventral nerve cords. Evolutionary Developmental Biology (EvoDevo) is an interdisciplinary field that seeks to understand how changes in development form the basis for variations in morphology and phenotypic evolution, including the genetic network underlying these processes. LÄS MER
4. Progression of RNA-sequencing to single-cell applications
Sammanfattning : New methods enable new discoveries. My time as a PhD student has run in parallel with the maturation of the RNA-seq method, and I have used it to discover basic properties of gene expression and transcriptomes. My part has been bioinformatics – the computer analysis of biological data. LÄS MER
5. Resolving the Genomic Complexity of Pediatric Acute Lymphoblastic Leukemia
Sammanfattning : Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer in the Nordic countries. Structural chromosomal rearrangements are a hallmark of ALL and represent key markers for diagnosis, risk stratification and prognosis. LÄS MER