Sökning: "Functional imaging"

Visar resultat 21 - 25 av 418 avhandlingar innehållade orden Functional imaging.

  1. 21. Direct observation of biomolecule adsorption and spatial distribution of functional groups in chromatographic adsorbent particles

    Författare :Anders Ljunglöf; Abraham Lenhoff; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biotechnology; Confocal microscopy; confocal Raman spectroscopy; protein adsorption; ligand distribution; visualization; imaging; Bioteknik; Bioengineering; Bioteknik; Surface Biotechnology; ytbioteknik;

    Sammanfattning : Confocal microscopy has been used as a tool for studying adsorption of biomolecules to individual chromatographic adsorbent particles. By coupling a fluorescent dye to protein molecules, their penetration into single adsorbent particles could be observed visually at different times during batch uptake. LÄS MER

  2. 22. Non-invasive Functional Neuroimaging for Localizing Epileptic Brain Activity

    Författare :Yazdan Shirvany; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Mathematical Dipole; Finite Element Method; Source localization; Structural Magnetic Resonance Imaging; Forward Problem; Inverse Problem; Particle Swarm Optimization; Non-invasive EEG; Somatosensory Evoked Potentials; Epileptic Spike; Functional Neuroimaging;

    Sammanfattning : Surgical therapy has become an important therapeutic alternative for patients with medically intractable epilepsy. Correct and anatomically precise localization of the epileptic focus, preferably with non-invasive methods, is the main goal of the pre-surgical epilepsy diagnosis to decide if resection of brain tissue is possible. LÄS MER

  3. 23. Cross-modal Imaging in Lung Research: From µCT dosimetry to synchrotron phase contrast microtomography biomechanical insights in preclinical lung injury models

    Författare :Richard Deyhle Jr; Malmö Medicinsk strålningsfysik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Thermoluminescent Dosimetry; Optically stimulated luminescence OSL ; Computed tomography CT ; 4DCT; Phantoms; Imaging; X-rays; pre-clinical models; Pre-clinical; dosimetry: physical basis; biomedical strain; lung injury; mechanical ventilation; inflammation; lung function; synchrotron; histology; acute respiratory distress syndrome ARDS ; Ventilator Inudced Lung Injury VILI ; Histology; Forced Oscillation Technique FOT ; Divergence Theorem; Registration techniques;

    Sammanfattning : Lung diseases continue to present a large burden to public health, especially in industrialized countries. For abetter understanding of the underlying patho-mechanisms in lung related diseases as well as for testing theefficacy of novel therapies, preclinical studies in animal models are indispensable. LÄS MER

  4. 24. MRI at 3 T of brain functions and fibre tracts adjacent to intracranial tumors

    Författare :Danielle van Westen; Lund Diagnostisk radiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; medical instrumentation; Klinisk fysiologi; radiologi; tomografi; medicinsk instrumentering; radiology; tomography; Clinical physics; Medicin människa och djur ; Medicine human and vertebrates ; somatosensory cortex; diffusion magnetic resonance imaging; neoplasms; Functional Magnetic Resonance Imaging;

    Sammanfattning : The aims of the studies were: to evaluate the spatial resolution of fMRI at 3 T by studying fingersomatotopy in area 3 b of the primary sensory area (Paper 1); to investigate the potential of fMRI at 3T as a clinical tool for preoperative evaluation of patients with intracranial tumors (Paper 2); to investigate the effect of glioma resection on the spatial extent of fMRI activation as compared to the normal within-subject variability (Paper 3); to determine whether the apparent diffusion coefficient (ADC) and fractional anisotropy (FA) can distinguish tumor-infiltrated edema of gliomas from pure edema of meningiomas and metastases (Paper 4). Results: Strict somatotopic organisation in the primary sensory cortex was shown in the group average; at the subject level the thumb was located laterally, anteriorly and inferiorly to the little finger in 94 % of subjects (Paper 1). LÄS MER

  5. 25. Functional brain imaging of sensorimotor dysfunction and restoration : investigations of discomplete spinal cord injury and deep brain stimulation for essential tremor

    Författare :Amar Awad; Johan Eriksson; Patric Blomstedt; Richard Levi; Lars Nyberg; Rick Helmich; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Sensorimotor control; fMRI; discomplete spinal cord injury; essential tremor; deep brain stimulation; cerebello-thalamo-cerebral circuit; Physiology; fysiologi; neurokirurgi; Neurosurgery; Neurology; neurologi; rehabiliteringsmedicin; Rehabilitation Medicine;

    Sammanfattning : The nervous system exists to generate adaptive behaviour by processing sensory input from the body and the environment in order to produce appropriate motor output, and vice versa. Consequently, sensorimotor dysfunction is the basis of disability in most neurological pathologies. LÄS MER