Sökning: "Eva Severinson"
Hittade 4 avhandlingar innehållade orden Eva Severinson.
1. Feedback Enhancement of Immune Responses by IgE, IgM, and IgG3 Antibodies
Sammanfattning : Antibodies can enhance or suppress the immune responses against their specific antigens. This phenomenon is known as antibody-mediated feedback regulation. We have studied the mechanisms underlying IgE-, IgM-, and IgG3-mediated enhancement of immune responses in mouse models using intravenous immunization. LÄS MER
2. Activation, adhesion and motility of B lymphocytes in health and disease
Sammanfattning : B cells can be activated by T cell-dependent stimuli, such as CD40 ligation and cytokines, which induce extensive proliferation, class switch recombination and somatic hypermutation.Epstein-Barr virus (EBV) can also induce B cell activation by mimicking T cell help through its main oncoprotein, latent membrane protein 1 (LMP-1). LÄS MER
3. Regulation of Immunoglobulin Isotype Switching and of the Germinal Center Response
Sammanfattning : After stimulation, B cells can undergo two types of genetic alteration in their immunoglobulin (Ig) genes: somatic hypermutation and class switch recombination (CSR), both of which are initiated by activation-induced cytidine deaminase (AID).Although class switching requires cell proliferation, the mechanism is partly unknown. LÄS MER
4. The Influence of Modality Combinations on Communication in Collaborative Virtual Environments
Sammanfattning : Although many studies have been performed on collaboration in multimodal interfaces not many of these have looked specifically on how the supported modalities influence the task solving strategies chosen and the communication between users solving a joint task in collaborative virtual environments. Therefore, the thesis studies performed aimed at shedding light on these aspects of multimodality. LÄS MER