Sökning: "Dock10"

Hittade 1 avhandling innehållade ordet Dock10.

1. 1. Activation, adhesion and motility of B lymphocytes in health and disease

   Författare :Natalija Gerasimcik; Eva Severinson; Victor Tybulewicz; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; B cells; activation; motility; IL-4; EBV; Dock10; Cdc42; Rac1 and Rac2; immunologi; Immunology;

   Sammanfattning : B cells can be activated by T cell-dependent stimuli, such as CD40 ligation and cytokines, which induce extensive proliferation, class switch recombination and somatic hypermutation.Epstein-Barr virus (EBV) can also induce B cell activation by mimicking T cell help through its main oncoprotein, latent membrane protein 1 (LMP-1). LÄS MER