Sökning: "Minghui He"

Hittade 1 avhandling innehållade orden Minghui He.

1. 1. Regulation of Immunoglobulin Isotype Switching and of the Germinal Center Response

   Författare :Minghui He; Eva Severinson; Jayanta Chaudhuri; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; immunologi; Immunology;

   Sammanfattning : After stimulation, B cells can undergo two types of genetic alteration in their immunoglobulin (Ig) genes: somatic hypermutation and class switch recombination (CSR), both of which are initiated by activation-induced cytidine deaminase (AID).Although class switching requires cell proliferation, the mechanism is partly unknown. LÄS MER