Sökning: "Rac1 and Rac2"

Hittade 2 avhandlingar innehållade orden Rac1 and Rac2.

1. 1. Activation, adhesion and motility of B lymphocytes in health and disease

   Författare :Natalija Gerasimcik; Eva Severinson; Victor Tybulewicz; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; B cells; activation; motility; IL-4; EBV; Dock10; Cdc42; Rac1 and Rac2; immunologi; Immunology;

   Sammanfattning : B cells can be activated by T cell-dependent stimuli, such as CD40 ligation and cytokines, which induce extensive proliferation, class switch recombination and somatic hypermutation.Epstein-Barr virus (EBV) can also induce B cell activation by mimicking T cell help through its main oncoprotein, latent membrane protein 1 (LMP-1). LÄS MER

3. 2. Signal transduction in human phagocytic cells during phagocytosis, oxidative activation and apoptosis

   Författare :Maria Forsberg; Emmanuelle Caron; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : Neutrophils and macrophages are professional phagocytic cells that play a crucial role in host defense against invading microorganisms. They bind to, internalize, and subsequently kill microbes with an arsenal of reactive oxygen metabolites and microbicidal agents. LÄS MER