Sökning: "CNS"

Visar resultat 6 - 10 av 589 avhandlingar innehållade ordet CNS.

  1. 6. Roles of PDGF for Neural Stem Cells

    Författare :Mia Enarsson; Karin Nilsson; Bengt Westermark; Peter Eriksson; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; CNS; stem cells; neuron; PDGF; proliferation; differentiation; ERK; microarray; transgenic mouse; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi;

    Sammanfattning : Stem cells are endowed with unique qualities: they can both self-renew and give rise to new mature cell types. Central nervous system (CNS) stem cells can give rise to neurons and glia. LÄS MER

  3. 7. Novel Immunotherapies and Immunoregulation in a Chronic Inflammatory Disease of the Central Nervous System

    Författare :Shahram Lavasani; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Neurologi; neurophysiology; neuropsychology; Neurology; Djurfysiologi; Animal physiology; probiotics; immunotherapy; CD1; T-cell; CNS; inflammation; EAE; MS; neuropsykologi; neurofysiologi;

    Sammanfattning : Multiple sclerosis (MS) is a chronic inflammatory disease of central nervous system (CNS) which is thought to arise from a breakdown of immunological tolerance in CD4 cells. The aim of this thesis is to improve our understanding of regulation mechanisms of T cell-dependent chronic inflammation in the CNS and explore ways to overcome the onset and progression of the disease, which can be an important step forward in the treatment of MS. LÄS MER

  4. 8. Genetic pathways controlling CNS development : The role of Notch signaling in regulating daughter cell proliferation in Drosophila

    Författare :Caroline Bivik Stadler; Stefan Thor; Jan-Ingvar Jönsson; Allison Bardin; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The human central nervous system (CNS) displays the greatest cellular diversity of any organ system, consisting of billions of neurons, of numerous cell sub-types, interconnected in a vast network. Given this enormous complexity, decoding the genetic programs controlling the multistep process of CNS development remains a major challenge. LÄS MER

  5. 9. Neurotoxicity of β-lactam antibiotics : experimental kinetic and neurophysiological studies

    Författare :Silvia E. Schliamser; Ragnar Norrby; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; benzylpenicillin; blood-brain barrier; ß-lactam antibiotics; CSF; CNS; EEG; imipenem cilastatin; FCE 22101; meningitis; neurotoxicity of; silent-second; thiopental; transport system; uraemia;

    Sammanfattning : The neurotoxic potential of intravenous administered benzylpenicillin (BPC) was studied in rabbits with intact blood-CNS barriers and rabbits with experimental E. coli meningitis. At onset of epileptogenic EEG activity or seizures, serum, CSF and brain tissue were collected for assay of BPC. LÄS MER

  7. 10. Neural Stem Cell Differentiation and Migration

    Författare :Anna Erlandsson; Karin Forsberg-Nilsson; Bengt Westermark; Christer Betsholtz; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; CNS; stem cells; neuron; PDGF; SCF; differentiation; migration; ERK; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; Medicinsk biokemi; Medical Biochemistry;

    Sammanfattning : Neural stem cells are the precursors of neurons, astrocytes and oligodendrocytes. During neural development, the division of stem cells takes place close to the lumen of the neural tube, after which they migrate to their final positions within the central nervous system (CNS). LÄS MER