Sökning: "Bronchoconstriction"

Visar resultat 21 - 25 av 27 avhandlingar innehållade ordet Bronchoconstriction.

  1. 21. Patients with asthma-like symptoms but negative asthma tests and patients with bronchial asthma

    Författare :Karin Ringsberg; Töres Theorell; Linköpings universitet; []
    Nyckelord :Asthma-like symptoms; bronchial asthma; coping; dyspnoea; education; hyperventilation; lung function; physical exercise; quality of life; MEDICINE; MEDICIN;

    Sammanfattning : Patients with asthma-like symptoms but with negative results in asthma tests have recently been identified. The symptoms are mainly triggered by strong odours, physical exercise and mental stress. These patients are often misdiagnosed and mistreated. They mostly have to find coping strategies by themselves. LÄS MER

  2. 22. Prostaglandin modulation of airway hyperresponsiveness and inflammation in murine models of asthma

    Författare :Linda Swedin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Allergic asthma is an inflammatory disease of the airways and is characterised by chronic inflammation, reversible bronchoconstriction and airway hyperresponsiveness (AHR). The cyclooxygenases (COXs) are key enzymes in the biosynthesis of prostaglandins, which have diverse physiological and pathological functions, and are also important modulators of inflammatory responses in the lung. LÄS MER

  3. 23. Endogenous and exogenous glucocorticoid effects in a model of allergic airway inflammation

    Författare :Susanna Kumlien Georén; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Airway; allergy; asthma; eosinophil; glucocorticoids; hypothalamus-pituitary-adrenal HPA axis; inflammation; nerve growth factor NGF ; neuroimmunology; psychoneuroimmunology; restraint; stress;

    Sammanfattning : Allergic asthma and rhinitis are inflammatory diseases of the airways. Allergic asthma is characterized by eosinophilic inflammation, reversible bronchoconstriction and airway hyperresponsiveness, whereas patients with rhinitis suffer from nasal inflammation, leading to rhinorrhea and nasal congestion. LÄS MER

  4. 24. Clinical studies of asthma phenotypes focusing on the role of the leukotrienes

    Författare :Per Gyllfors; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :>asthma; aspirin intolerance; leukotrienes; leukotriene D4 responsiveness; methacholine responsiveness; exhaled nitric oxide;

    Sammanfattning : Inflammation in the airways in connection to asthma is a complex phenomenon and the mechanisms underlying the associated clinical symptoms involve the interaction of many different kinds of cells and mediators, giving rise to different phenotypes. The aim of the present thesis was to investigate the molecular and cellular mechanisms that results in two of these phenotypes, i. LÄS MER

  5. 25. Studies on neuroimmune interactions in allergic inflammation with focus on neurotrophins

    Författare :Cecilia Kemi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Allergic inflammation; neuroimmune interaction; neurotrophins; smooth muscle cells; stress;

    Sammanfattning : Allergic asthma is a chronic airway disease characterized by an eosinophilic inflammation, bronchoconstriction, increased mucus production and bronchial hyperreactivity. The disease involves several mediators and cell types and is associated with a Th2-mediated immune response. Stress is a factor reported to deteriorate the allergic inflammation. LÄS MER