Sökning: "tricyclic antidepressants"
Visar resultat 1 - 5 av 16 avhandlingar innehållade orden tricyclic antidepressants.
1. On the efficacy and prescription of serotonin reuptake inhibitors
Sammanfattning : This thesis addresses several controversial issues regarding commonly used antidepressants, including selective serotonin reuptake inhibitors (SSRIs), serotonin and noradrenaline reuptake inhibitors (SNRIs), and tricyclic antidepressants (TCAs). To this end, patient-level data from 28 placebo-controlled trials on SSRIs and 13 corresponding trials on the SNRI duloxetine, were requested and obtained. LÄS MER
2. Acute lung failure induced by tricyclic antidepressants : an experimental evaluation
Sammanfattning : The tricyclic antidepressant drugs (TCA) have, over the years, been reported to be able to cause adult respiratory distress syndrome (ARDS)/acute lung injury in connection with overdose, and are currently among the most common cause of self-poisoning. Approximately 10% of all TCA overdose patients develop ARDS, and the treatment of these patients, irrespective of the event causing ARDS, is mainly supportive. LÄS MER
3. Bipolar disorders: Subtypes, treatments, and health inequalities
Sammanfattning : This thesis comprises five studies based on prospective, longitudinal data from the Swedish national quality register BipoläR. Study I examined the differences between bipolar subtype I and II with respect to clinical features, course of illness, comorbidity, and socioeconomic factors. LÄS MER
4. Therapy-resistant enuresis : In search of new therapies and prognostic markers
Sammanfattning : A large minority of children with enuresis do not respond to treatment with either desmopressin or the enuresis alarm. Anticholinergics have not proven as successful as expected. The fourth evidence-based treatment of enuresis, the tricyclic antidepressant imipramine, is cardiotoxic when overdosed, which has led to diminished use. LÄS MER
5. Formation of active metabolites by demethylation and hydroxylation of tricyclic antidepressants in man
Sammanfattning : .... LÄS MER