Sökning: "aspirin intolerance"

Hittade 2 avhandlingar innehållade orden aspirin intolerance.

  1. 1. Clinical studies of asthma phenotypes focusing on the role of the leukotrienes

    Författare :Per Gyllfors; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :>asthma; aspirin intolerance; leukotrienes; leukotriene D4 responsiveness; methacholine responsiveness; exhaled nitric oxide;

    Sammanfattning : Inflammation in the airways in connection to asthma is a complex phenomenon and the mechanisms underlying the associated clinical symptoms involve the interaction of many different kinds of cells and mediators, giving rise to different phenotypes. The aim of the present thesis was to investigate the molecular and cellular mechanisms that results in two of these phenotypes, i. LÄS MER

  2. 2. Nasal and bronchial testing as well as treatment of patients with airway hyperresponsiveness and inflammation focusing on the united airway concept

    Författare :Anders Ehnhage; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Allergic and non-allergic rhinitis and asthma is a global health problem on the increase that causes major illness and disability worldwide, and also results in a large financial burden on society. This thesis contains six papers, based on four different clinical studies on humans with allergic as well as non-allergic airways inflammation, such as neutrophil inflammation caused by exposure to swine dust, as well as chronic rhinosinusitis and concomitant asthma with and without NSAID intolerance. LÄS MER