Sökning: "Biomedicinska vetenskaper allmänt"

Visar resultat 6 - 10 av 14 avhandlingar innehållade orden Biomedicinska vetenskaper allmänt.

  1. 6. Characterization of fibroblast phenotypes in human airway remodeling

    Författare :Kristoffer Larsen; Lungbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine human and vertebrates ; Medicin människa och djur ; remodeling; General biomedical sciences; Biomedicinska vetenskaper allmänt ; fibrocytes; proteoglycans; Asthma; fibroblasts;

    Sammanfattning : Wound healing that precedes scar formation may be unbalanced under pathological conditions leading to structural changes of the tissue. At the moment, the mechanisms behind this unbalance are unclear. When these changes occur in internal organs such as the lung, they may result in organ dysfunction with fatal consequences for the patient. LÄS MER

  3. 7. Helicobacter pylori binding to gastric mucins and host glycosylation changes after inoculation

    Författare :Sara Lindén; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicinska vetenskaper allmänt ; General biomedical sciences; host-parasite interactions; H. pylori adhesin; mucin; Lewis antigen;

    Sammanfattning : Helicobacter pylori may cause gastritis, gastric/duodenal ulcer and gastric cancer. During infection, most H. pylori are found in the gastric mucus layer, but some are attached to, or have penetrated, epithelial cells. The aim of this study is to characterize the binding of H. LÄS MER

  4. 8. Bioactive Proteins in Bovine Milk - Studies on Glutathione Peroxidase, Lactoferrin and Immunoglobulins

    Författare :Helena Lindmark Månsson; Kemiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; General biomedical sciences; Biokemisk teknik; Biochemical technology; thermal stability; milk processability; selenium; antioxidants; immunoglobulin; lactoferrin; Milk; glutathione peroxidase; Biomedicinska vetenskaper allmänt ; Biochemistry; Metabolism; Biokemi; metabolism;

    Sammanfattning : Many proteins in bovine milk exhibit specific biological activity in addition to their established nutritional value as source of protein. Examples of such bioactive proteins are extracellular glutathione peroxidase, lactoferrin and immunoglobulins. LÄS MER

  5. 9. Proteoglycan Lectin Domain Interactions in Extracellular Matrix Assembly

    Författare :Anders Olin; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicinska vetenskaper allmänt ; General biomedical sciences; crystal structure; network formation; collagen IX; N-glycans; PRELP; cross-linking; fibulin-2; lectin; G3; ECM; proteoglycan;

    Sammanfattning : This thesis focuses on the C-terminal G3 region of the large aggregating proteoglycans that are found in complex with hyaluronan in the extracellular matrix. The G3 region contains a C-type lectin domain that binds different extracellular matrix proteins playing an integral role in tissue organization during development and remodeling. LÄS MER

  7. 10. Contact activation on bacterial surfaces - a virulence mechanism

    Författare :Kristin Persson; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; General biomedical sciences; Biomedicinska vetenskaper allmänt ; sepsis; infection; S. aureus; S. typhimurium; E. coli; curli; fibrinopeptides; fibrinogen; Coagulation; contact system;

    Sammanfattning : Life-threatening conditions from bacterial infections are a major clinical problem. During a severe infection, the host responds by a massive release of pro-inflammatory mediators together with a systemic activation of systems such as the coagulation, fibrinolytic, and complement systems. LÄS MER