Sökning: "Analytical Chemistry"
Visar resultat 31 - 35 av 726 avhandlingar innehållade orden Analytical Chemistry.
31. Molecular Imaging of Diabetic Kidney Tissue and Binding Studies of Proinsulin C-peptide
Sammanfattning : Diabetic kidney disease is a serious complication of diabetes with a complex and incompletely understood pathology. In this work, the molecular changes in diabetic rat kidneys at a very early disease stage were studied using nanospray desorption electrospray ionisation mass spectrometry imaging. LÄS MER
32. Development of Field-adapted Analytical Methods for the Determination of New Antimalarial Drugs in Biological Fluids
Sammanfattning : This thesis deals with the development of analytical methods for the determination of new antimalarial drugs in biological fluids. The goal was to develop methods that facilitate clinical studies performed in the field, such as capillary blood sampling onto sampling paper. LÄS MER
33. Advances in analytical methodologies for studies of the platinum metallome in malignant cells exposed to cisplatin
Sammanfattning : The scientific progress about the important chemotherapeutic drug substance cisplatin (CDDP) and its function has often been rendered by data difficult to interpret, and still many questions about its mode of action remains to be clarified by the scientific community. However, studies of CDDP possess a high complexity due to; i) low intracellular concentration, ii) many potential biomolecule targets, iii) poor or unknown stability of the intact drug and its biomolecule adducts and iv) complex and varying sample matrices. LÄS MER
34. Creating Ultrafast Biosensors for Neuroscience
Sammanfattning : Neuronal communication is the basis for all our brain function and relies on regulated exocytosis, a cell function that involves release of quantal amounts of neurotransmitters into the gap space between interconnected neurons to serve as chemical signals. To study exocytosis, which is a fast process that occurs on the timescale of sub-milliseconds to milliseconds, a toolbox of analytical methods has been developed where the electrochemical based techniques offer quantitative and sufficient high temporal recording speed. LÄS MER
35. Electrokinetic devices from polymeric materials
Sammanfattning : There are multiple applications for polymers: our bodies are built of them, plastic bags and boxes used for storage are composed of them, as are the shells for electronics, TVs, computers, clothes etc. Many polymers are cheap, and easy to manufacture and process which make them suitable for disposable systems. LÄS MER
