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  1. 1. Evaluation of MRI as a diagnostic method in biliary tract conditions

    Författare :Katarina Håkansson; Avdelningen för klinisk kemi och farmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk fysiologi; radiologi; tomografi; medicinsk instrumentering; medical instrumentation; tomography; radiology; Clinical physics; T2; T1; Relaxation rate; Gallbladder bile; Acute cholangitis; Biliary duct injury; Biliary duct disease; Cholecystectomy; Bile duct; Acute cholecystitis; ERCP; Ultrasound; MRI; MRCP;

    Sammanfattning : The diagnostic value of modern fast pulse sequences and breath-hold technique was evaluated in a prospective study of patients with suspected biliary diseases. The cost-effectiveness of MRI compared to ultrasound was calculated. LÄS MER

  3. 2. Studies of ulcerative colitis with concomitant primary sclerosing cholangitis : Beyond the clinical phenotype

    Författare :Johan Vessby; Marie Carlson; Maria Lampinen; Mikael Åberg; Fredrik Rorsman; Björn Lindkvist; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IBD; PSC; ulcerative colitis; PSC-UC; immunology; eosinophils; T cells; tissue factor; proteomics; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Inflammatory bowel disease (IBD) is a group of chronically relapsing immune-related disorders, engaging the gastrointestinal tract. Symptoms vary depending on inflammatory phenotype, but may include diarrhoea, bowel pain and weight loss. The two most common entities are Crohn's disease and ulcerative colitis (UC). LÄS MER

  4. 3. Gallbladder and pancreatic disease in patients with primary sclerosing cholangitis

    Författare :Karouk Said; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cholecystitis; gallbladder; ejection fraction; magnetic resonance imaging; pancreatic duct; chronic pancreatitis; thioredoxin; Immunohistochemical staining;

    Sammanfattning : The aims of this study were to assess the occurrence of gallbladder abnormalities and dysfunction, to evaluate clinically useful biomarkers for premalignancy and malignancy in gallbladder epithelium and to assess presence of pancreatic duct changes and early pancreatic abnormalities in patients with primary sclerosing cholangitis (PSC). In paper I and III we investigated presence of gallbladder abnormalities in 286 patients with PSC treated at Karolinska University Hospital, Huddinge, between 1970 and 2005. LÄS MER

  5. 4. Cancer and reconstructive surgery in Inflammatory bowel disease

    Författare :Maie Abdalla; Pär Myrelid; Johan D Söderholm; Roland Andersson; Kalle Landerholm; Yves Panis; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Inflammatory bowel disease; Colorectal cancer; IRA; IPAA; Primary sclerosing cholangitis;

    Sammanfattning : Ulcerative colitis (UC) is a chronic inflammatory disease that affects the colon. According to the literature, some thirty percent of UC patients may require a subtotal colectomy and ileostomy due to failure of medical treatment, acute toxic colitis or dysplasia/cancer diagnosis. LÄS MER

  7. 5. Mechanisms of liver allograft rejections

    Författare :Xupeng Ge; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Liver transplantation; acute rejection; antibody; biliary epithelial cell; sinusoidal endothelial cell; cholangitis; toll-like receptor;

    Sammanfattning : Liver transplantation (M) has become a standard treatment for many end-stage liver diseases. However, acute rejections still occur in about half of the liver transplant recipients even treated with a combination of different modem immunosuppressants. LÄS MER