Sökning: "17?-estradiol"

Visar resultat 16 - 20 av 37 avhandlingar innehållade ordet 17?-estradiol.

  1. 16. Sex Differences in Cardiac and Cerebral Damage after Hypovolemic Cardiac Arrest

    Författare :Egidijus Semenas; Sten Rubertsson; Lars Wiklund; Ala Nozari; Sven Erik Gisvold; Uppsala universitet; []
    Nyckelord :Cardiopulmonary resuscitation; sex; haemorrhage; neuronal damage; estradiol; hypertonic saline; nitric oxide; methylene blue; MEDICINE; MEDICIN; Anaesthesiology and Intensive Care; Anestesiologi och intensivvård;

    Sammanfattning : Resuscitation from haemorrhagic shock and the subsequent circulatory arrest remains a major clinical challenge in the care of trauma patients. Numerous experimental studies in sexually mature animals have shown a gender dimorphism in response to trauma and haemorrhagic shock. LÄS MER

  3. 17. Antitumor Activities of 2-Methoxyestradiol on Cervical and Endometrial Cancers In Vitro and In Vivo

    Författare :Li Li; Xin Fu; Mats Brännström; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics and gynaecology; 2-Methoxyestradiol; HeLaS3 cells; HEC-1-A cells; RL-95-2 cells; cervical cancer; endometrial cancer; Obstetrik och kvinnosjukdomar; Obstetrics and women s diseases; Obstetrik och kvinnosjukdomar;

    Sammanfattning : 2-Methoxyestradiol (2-ME), a metabolite of 17β-estradiol, is a potent antitumor and antiangiogenesis agent in vitro and in vivo. This study aimed to investigate the effects of 2-ME on human cervical and endometrial cancers in vitro and in vivo. LÄS MER

  4. 18. Growth Hormone and Gender. Studies in Healthy Adults and in Patients with Growth Hormone Disorders

    Författare :Britt Edén Engström; Uppsala universitet; []
    Nyckelord :Medical sciences; Growth hormone; gender; ambulation; oral contraceptives; epinephrine; GH treatment; age; E2-implant; IGF-I; octreotide; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Sammanfattning : The use of a new, more sensitive immunoassay for growth hormone (GH) revealed that the serum levels in men were lower than expected in sera drawn ambulatory in the morning after an overnight fast and that the gender difference was more than 10 times greater than reported. These observations led to a more thorough study on the impact of gender and sex steroids on the levels of GH and other hormones in ambulatory morning samples and over a 24-hour period. LÄS MER

  5. 19. The juvenile three-spined stickleback : model organism for the study of estrogenic and androgenic endocrine disruption in laboratory and field

    Författare :Edda Hahlbeck; Bengt-Erik Bengtsson; Poul Bjerregaard; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; endocrine disruption; Terrestrial; freshwater and marine ecology; Terrestisk; limnisk och marin ekologi;

    Sammanfattning : Industrial and domestic sewage effluents have been found to cause reproductive disorders in wild fish, often as a result of the interference of compounds in the effluents with the endocrine system. This thesis describes laboratory-based exposure experiments and a field survey that were conducted with juveniles of the three-spined stickleback, Gasterosteus aculeatus. LÄS MER

  7. 20. Estrogen actions in the growth plate cartilage

    Författare :Maryam Iravani; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Estrogens may influence bone growth locally or systemically via the estrogen receptors alpha (ERα), beta (ERβ) and G protein-coupled estrogen receptor 1 (GPER-1). In Paper I, our study showed that the treatment of ovariectomized C57BL/6 mice with a selective ERα agonist 1,3,5-tris(4-hydroxyphenyl)-4-propyl-1H-pyrazole (PPT) reduced growth plate height and hypertrophic zone height suggesting that the effect was induced via ERα. LÄS MER