Sökning: "γδ T cell"

Visar resultat 1 - 5 av 17 avhandlingar innehållade orden γδ T cell.

  1. 1. Human intestinal T lymphocytes : a comparative analysis of phenotype and function in normal and inflamed mucosa

    Detta är en avhandling från Umeå : Umeå universitet

    Författare :Silvia Melgar; Umeå universitet.; [2002]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human intestinal mucosa; intraepithelial lymphocyte; lamina propria lymphocyte; γδ T cell; regulatory T cell; cytotoxicity; cytokine; basal lymphoid aggregate; ulcerative colitis; Crohn s disease;

    Sammanfattning : The epithelial lining of the gut must allow immediate contact with beneficial components as nutrients and normal microflora. At the same time it runs the constant risk of attack from pathogenic microbes and noxious agents. LÄS MER

  2. 2. Vγ9Vδ2 T cells - response to P. falciparum-derived phosphoantigens and potential for use in colon cancer immunotherapy 

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Chenxiao Liu; Uppsala universitet.; [2018]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medical Cell Biology; Medicinsk cellbiologi;

    Sammanfattning : Vγ9Vδ2 T cell is the dominant circulating γδ T cell subset in humans, can expand massively upon malaria infection and are cytotoxic to cancer cells. Vγ9Vδ2 T cells are stimulated by phosphoantigens, primarily isoprenoid pyrophosphates like isopentenyl pyrophosphate and (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate (HMBPP). LÄS MER

  3. 3. Human intraepithelial lymphocytes : a comparative study of phenotype, morphology, and functional properties of intraepithelial lymphocytes in gut and oral mucosa

    Detta är en avhandling från Umeå : Umeå universitet

    Författare :Carina Lundqvist; Umeå universitet.; [1995]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human intraepithelial lymphocytes; alimentary tract; intestinal epithelium; gut luminal antigens; gingiva; γδ T cells; immunoelectron microscopy; cytokine mRNA; RT-PCR; extrathymic T cell maturation; RAG-1; periodontitis; mucosal immune system; CD4-CD8- αβ T cells; CD8 γδ T cells;

    Sammanfattning : Human intraepithelial lymphocytes (IEL) constitute a unique cell population situated in the first line of defense of the alimentary tract. Here they are continuously exposed to a massive antigenic load of high complexity. However, different conditions prevail along the alimentary tract. LÄS MER

  4. 4. Expansion of circulatory Vγ9Vδ2 T cells in tularemia and Pontiac fever, two intracellular bacterial diseases with widely different clinical expression

    Detta är en avhandling från Umeå : Klinisk mikrobiologi

    Författare :Michal Kroca; Umeå universitet.; [2003]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; Francisella tularensis; Gamma-delta T cell; Legionella; Legionellosis; Lymphocyte; T cell Tularemia; Immunologi; MEDICINE Microbiology; immunology; infectious diseases Immunology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Immunologi; immunologi; Immunology;

    Sammanfattning : Although well established that human Vγ9Vδ2 T cells may expand in circulation during intracellular bacterial infections, most underlying studies included only a few cases and only some diseases had been studied so far. In tularemia, a severe invasive disease, only one patient had been described. LÄS MER

  5. 5. Butyrophilin- and Butyrophilin-like genes and their role in epithelial cell-intraepithelial T lymphocyte cross-talk

    Detta är en avhandling från Umeå : Klinisk mikrobiologi

    Författare :Cristina Lebrero-Fernandez; Göteborgs universitet.; Gothenburg University.; [2016]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Butyrophilin-like Btnl ; Butyrophilin Btn ; Intraepithelial lymphocytes IELs ; Mucosal immunity; Intestinal epithelial cells; γδ T cells; Intestinal inflammation; Colon cancer; Ulcerative colitis;

    Sammanfattning : More than 50% of our immune system is located in the gut. The intestinal epithelium, which forms an interface between the organism and the environment, harbors intraepithelial lymphocytes (IELs) that comprise a mixture of conventional αβ T cells and unconventional αβ- and γδ T cells. LÄS MER