Sökning: "virulence"

Visar resultat 6 - 10 av 464 avhandlingar innehållade ordet virulence.

  1. 6. Identification of new virulence factors in Francisella tularensis

    Författare :Anna-Lena Forslund; Åke Forsberg; Elisabeth Carniel; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Francisella tularensis; regulation; virulence; Hfq; DsbA; type IV pili; membrane; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : Francisella tularensis, the causative agent of tularemia, is a highly virulent bacterium with an infection dose of less than ten bacteria. The ability of a pathogen to cause infection relies on different virulence mechanisms, but in Francisella tularensis relatively few virulence factors are known. Two F. LÄS MER

  3. 7. The impact of Staphylococcus aureus surface proteins on virulence

    Författare :Niklas Palmqvist; Göteborgs universitet; []
    Nyckelord :Staphylococcus aureus; septic arthritis; sepsis; virulence; cell wall-anchored proteins; surface proteins; fibrinogen.;

    Sammanfattning : Staphylococcus aureus is an important pathogen in humans with the potential to cause life-threatening invasive infections, including sepsis and septic arthritis. The pathogenicity of S. aureus depends on the expression of a variety of virulence factors. LÄS MER

  4. 8. Small Molecules as Tools in Biological Chemistry : Effects of Synthetic and Natural Products on the Type III Secretion System

    Författare :Caroline E. Zetterström; Mikael Elofsson; Samuel I. Miller; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Type III secretion; salicylidene acylhydrazide; virulence-blocker; virulence; inhibitor; target identification; neohopeaphenol A; Yersinia pseudotuberculosis; Pseudomonas aeruginosa; Escherichia coli; biologisk kemi; biological chemistry;

    Sammanfattning : The increasing use of antibiotics has led to a huge problem for society, as some bacteria have developed resistance towards many of the antibiotics currently available. To help find solutions to this problem we studied small molecules that inhibit bacterial virulence, the ability to cause disease. LÄS MER

  5. 9. Analysis of the molecular interplay between Streptococcus pyogenes and its human host

    Författare :Björn Johansson; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; bacteriology; virology; mycology; Biomedicinska vetenskaper allmänt ; Regulation; General biomedical sciences; IdeS; Enzyme; Virulence factors; Virulence; Bacteria; Streptococci; bakteriologi; virologi; mykologi; GAS; Protein; Mikrobiologi;

    Sammanfattning : The common human pathogen Streptococcus pyogenes is the causative agent of numerous mild and severe clinical conditions. It expresses a number of secreted or cell wall-anchored proteins that modulate the human immune system and facilitate colonization and spread of the pathogen in the human host. During S. LÄS MER

  7. 10. Virulence mechanisms of pathogenic Yersinia : aspects of type III secretion and twin arginine translocation

    Författare :Moa Lavander; Åke Forsberg; George Salmond; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Yersinia pestis; Yersinia pseudotuberculosis; bacterial pathogenesis; type III secretion; twin arginine translocation; virulence mechanisms; YscU; YscP; YscF; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : The pathogenic bacteria Yersinia pestis and Y. pseudotuberculosis are related to the degree where the former is considered a subspecies of the latter, and still they cause disease of little resemblance in humans. Y. pestis is the causative agent of lethal bubonic and pneumonic plague, while Y. LÄS MER