Sökning: "virulence mechanisms"

Visar resultat 16 - 20 av 144 avhandlingar innehållade orden virulence mechanisms.

  1. 16. RsbX and stress response in Listeria monocytogenes

    Författare :Ana Henriques de Oliveira; Jörgen Johansson; Cormac Gahan; Umeå universitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Listeria monocytogenes; SigB; stressosome; RsbX; phosphorylation; growth; competitiveness; motility; energetic cost; homeostasis; stress response; virulence; invasion; molekylärbiologi; Molecular Biology; mikrobiologi; Microbiology;

    Sammanfattning : Listeria monocytogenes is a ubiquitous foodborne Gram-positive bacterium. Despite being mainly a soil bacterium, it can reach the food processing environment and contaminate food destined for human consumption, causing outbreaks. LÄS MER

  3. 17. It Takes Two to Tango : Bacterial heterogeneity and host cell features govern Salmonella infection

    Författare :Viktor Ek; Mikael E. Sellin; Francisco García del Portillo; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Salmonella; swimming; swim pattern; targetting; virulence; invasion; host-pathogen interactions; epithelium; epithelial cells; macrophages; monocytes; monolayer; flagella; genome; genetic; barcoding; discreet-invasion; shape; morphology; antibiotics; persistence; Mikrobiologi; Microbiology;

    Sammanfattning : Salmonella enterica serovar Typhimurium (S.Tm) causes enterocolitis with significant worldwide morbidity and mortality. The general aim of this thesis is to investigate variation in host cell invasion mechanisms used by S.Tm across different host cell contexts, as well as the influence of bacterial cell-cell heterogeneity on invasion-relevant S. LÄS MER

  4. 18. Virulence in Plasmodium falciparum malaria : mechanisms of PfEMP1-mediated rosetting

    Författare :Davide Angeletti; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Malaria is one of the most important infectious diseases in the world and the Plasmodium falciparum parasite is the causative agent of most of the severe cases. The pathogenesis of the disease is complex but sequestration and hence microvascular obstruction is associated with virulence of the parasite. LÄS MER

  5. 19. YopD translocator function in Yersinia pseudotuberculosis type III secretion

    Författare :Tiago R. D. Costa; Matthew S. Francis; William D. Picking; Umeå universitet; []
    Nyckelord :Y. pseudotuberculosis; T3SS; translocon; YopD; coiled-coil; effector delivery; regulation; virulence; mikrobiologi; Microbiology;

    Sammanfattning : Type III secretion systems (T3SS) are a common feature of Gram-negative bacteria, allowing them to inject anti-host effectors into the interior of infected eukaryotic cells. By this mechanism, these virulence factors help the bacteria to modulate eukaryotic cell function in its favor and subvert host innate immunity. LÄS MER

  7. 20. Enterococci in Swedish intensive care units : studies on epidemiology, mechanisms of antibiotic resistance and virulence factors

    Författare :Anita Hällgren; Arnfinn Sundsfjord; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : The purpose of this thesis was to study enterococci in Sweden, their resistance to antibiotics in general and high-level gentamicin resistance (HLGR) in particular, with a special focus on the ICU setting. Dynamics of rectal colonisation during prolonged intensive care unit (ICU) stay was assessed. LÄS MER