Sökning: "trauma förlust"

Visar resultat 1 - 5 av 9 avhandlingar innehållade orden trauma förlust.

  1. 1. DNA repair and the p53 pathway in ischemic and traumatic brain injury

    Författare :Gregor Tomasevic; Neurokirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuronal death; DNA repair; knock-out mice; XPA; p53; mRNA; hippocampus; preconditioning; hypothermia; trauma; Brain; ischemia; neurobehavior; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

    Sammanfattning : Ischemic and traumatic brain damage are major causes of disability and death. While much effort has been spent to develop pharmacological treatments for these conditions, no neuroprotective drugs are in clinical use. LÄS MER

  3. 2. Experimental Traumatic Brain Injury and Cell Death - in vivo and in vitro aspects

    Författare :Gustav Mattiasson; Sektion IV; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurofysiologi; neuropsychology; Neurology; uncoupling protein; mitochondrial permeability transition; cerebral blood flow; functional outcome; cell death; mitochondria; hippocampus; preconditioning; trauma; Brain; ischemia; neuropsykologi; Neurologi; neurophysiology;

    Sammanfattning : Traumatic and ischemic brain damage are major causes of disability and death. While much effort has been spent on developing pharmacological treatments for these conditions, no neuroprotective drugs are in clinical use. LÄS MER

  4. 3. Physiological and clinical aspects of change in microvascular permeability

    Författare :Johan Persson; Anestesiologi och intensivvård; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dextran; exercise; fluid therapy; gelatin; hydroxyethyl starch; Anaesthesiology; intensivvård; intensive care; Anestesiologi; crystalloids; colloids; Albumin; Capillary filtration coefficient;

    Sammanfattning : Microvascular permeability is important for exchange of fluids and proteins in health and in disease. Permeability increases in critical illness, such as during sepsis/SIRS and after trauma, and may be affected by drugs. Increased permeability causes oedema and hypovolaemia. LÄS MER

  5. 4. Engineering 3D degradable pliable scaffolds for adipose tissue regeneration : Advancing cell-material interactions by understanding the influence from thermal, chemical, mechanical properties and scaffold design

    Författare :Shubham Jain; Anna Finne-Wistrand; Kamal Mustafa; Mikael Hedenqvist; Lauren Flynn; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Degradable polymers; 3D scaffolds; adipose tissue regeneration; cell-material interaction; Fiber- och polymervetenskap; Fibre and Polymer Science;

    Sammanfattning : In soft tissue defects that arise due to trauma, tumor resections and complex burns, a significant loss in adipose tissue remains a considerable challenge due to the insufficient regenerative capacity of the tissue. This thesis focuses on assessing cell-material interactions between degradable 3D polymer scaffolds with different designs and adipose tissue-derived stem cells. LÄS MER

  7. 5. Vascular effects of prostacyclin in cat skeletal muscle and in the traumatised rat brain

    Författare :Peter Bentzer; Anestesiologi och intensivvård; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reflection coefficient; cerebral blood flow; hydraulic conductivity; oedema; capilary filtration coefficient; endothelin-1; ATP-dependent potassium channels; Physiology; Fysiologi;

    Sammanfattning : Disturbances in microvascular function may be important for tissue damage in many disease states. Prostacyclin, a substance produced by endothelial cells, is important for the maintenance of normal vascular homeostasis and is a potential drug for treatment of microvascular dysfunction, but indications and optimal dosage remains to be established. LÄS MER