Sökning: "ATP-dependent potassium channels"

Hittade 3 avhandlingar innehållade orden ATP-dependent potassium channels.

  1. 1. Vascular effects of prostacyclin in cat skeletal muscle and in the traumatised rat brain

    Författare :Peter Bentzer; Anestesiologi och intensivvård; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reflection coefficient; cerebral blood flow; hydraulic conductivity; oedema; capilary filtration coefficient; endothelin-1; ATP-dependent potassium channels; Physiology; Fysiologi;

    Sammanfattning : Disturbances in microvascular function may be important for tissue damage in many disease states. Prostacyclin, a substance produced by endothelial cells, is important for the maintenance of normal vascular homeostasis and is a potential drug for treatment of microvascular dysfunction, but indications and optimal dosage remains to be established. LÄS MER

  3. 2. Aspects on the modulation of potassium channels in insulin-producing beta-cells

    Författare :Zuheng Ma; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :islets of Langerhans; over-stimulation; diazoxide; exocytosis; proteasome; microarray; Kv1.1.;

    Sammanfattning : This thesis attempts to further clarify mechanisms behind the negative effects of overstimulation and the beneficial effect of β-cell rest. For this purpose diazoxide - opener of K+-ATP channels, which reversibly inhibits glucose-induced insulin secretion, was used as a probe. LÄS MER

  4. 3. The importance of nitric oxide availability in myocardial ischemia-reperfusion injury : regulatory roles of arginase, L-arginine and tetrahydrobiopterin

    Författare :Yahor Tratsiakovich; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background. Maintenance of nitric oxide (NO) availability is crucial for cardiovascular homeostasis and protection against myocardial ischemia-reperfusion (IR) injury. LÄS MER