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Visar resultat 1 - 5 av 172 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Transforming growth factor-ß : receptors and signal transduction

    Författare :Petra Franzén; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  3. 2. Insulin-like Growth Factor System: functional role and regulation in carcinomas

    Författare :Ann Rosendahl; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancerology; oncology; Cytology; PTEN; Transforming Growth Factor-beta; Insulin-like Growth Factor; Renal Cell Carcinoma; Cytologi; onkologi; cancer; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Sammanfattning : The insulin-like growth factor (IGF) system demonstrates numerous actions during neoplastic growth and is therefore an interesting target with potential clinical implications. While numerous studies have established important roles of the IGF system in regulating cellular growth and survival of several tumor forms, very limited reports exist regarding its role in renal cell carcinoma (RCC). LÄS MER

  4. 3. Pancreatic Growth and Secretion. An Experimental Study on Growth Factors in Rat and Mouse

    Författare :Claes Hjalmarsson; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oncology; Cytology; PBD; insulin; B-cells; bile; pancreatic cancer; intestine; secretion; pancreas; proliferation; tyrphostins; CCK; epidermal growth factor; transforming growth factor alpha; cancerology; Cytologi; onkologi; cancer; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi;

    Sammanfattning : The pancreas is a central organ in the digestion of food as well as in glucose metabolism. Its two major functions are exocrine and endocrine secretion. LÄS MER

  5. 4. Transforming growth factor a in human hematopoietic cells

    Författare :Thomas M. Walz; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : TGF-a, transforming growth factor a, is a potent growth factor belonging to the family of EGF (epidermal growth factor) -related proteins. Binding to the same receptor as EGF it has a ubiquitous repertoire of target cells, including, mesenchymal, epithelial and neuronal cells. LÄS MER

  7. 5. Studies of transforming growth factor alpha in normal and abnormal growth

    Författare :Anna-Lotta Hallbeck; Åke Wasteson; Thomas Walz; Annelie Lindström; Carl-Henric Heldin; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TGF-alpha; HER; EGFR; synovia; synovial sarcoma; RA; synovitis; Medical cell biology; Medicinsk cellbiologi;

    Sammanfattning : Regulation of growth is of fundamental importance for development of the organism and to maintain health. The induction of cell proliferation and matrix production are influenced by several different signaling systems, most importantly by growth factors. LÄS MER